The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
| Contributors |
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viii | |
| Foreword |
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xiii | |
| Introduction |
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Rationale, potentials, and promise of systematic reviews |
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3 | (20) |
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| Part I: Systematic reviews of controlled trials |
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Principles of and procedures for systematic reviews |
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23 | (20) |
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Problems and limitations in conducting systematic reviews |
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43 | (26) |
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Identifying randomised trials |
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69 | (18) |
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Assessing the quality of randomised controlled trials |
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87 | (22) |
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Obtaining individual patient data from randomised controlled trials |
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109 | (13) |
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Assessing the quality of reports of systematic reviews: the QUOROM statement compared to other tools |
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122 | (21) |
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| Part II: Investigating variability within and between studies |
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Going beyond the grand mean: subgroup analysis in meta-analysis of randomised trials |
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143 | (14) |
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Why and how sources of heterogeneity should be investigated |
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157 | (19) |
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Analysing the relationship between treatment benefit and underlying risk: precautions and recommendations |
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176 | (13) |
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Investigating and dealing with publication and other biases |
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189 | (22) |
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| Part III: Systematic reviews of observational studies |
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Systematic reviews of observational studies |
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211 | (17) |
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Systematic reviews of evaluations of prognostic variables |
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228 | (20) |
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Systematic reviews of evaluations of diagnostic and screening tests |
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248 | (37) |
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| Part IV: Statistical methods and computer software |
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Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis |
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285 | (28) |
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Effect measures for meta-analysis of trials with binary outcomes |
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313 | (23) |
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336 | (11) |
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347 | (26) |
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| Part V: Using systematic reviews in practice |
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Applying the results of systematic reviews at the bedside |
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373 | (13) |
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Numbers needed to treat derived from meta-analyses: pitfalls and cautions |
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386 | (14) |
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Using systematic reviews in clinical guideline development |
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400 | (10) |
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Using systematic reviews for evidence based policy making |
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410 | (9) |
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Using systematic reviews for economic evaluation |
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419 | (10) |
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Using systematic reviews and registers of ongoing trials for scientific and ethical trial design, monitoring, and reporting |
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429 | (18) |
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| Part VI: The Cochrane Collaboration |
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The Cochrane Collaboration in the 20th century |
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447 | (12) |
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The Cochrane Collaboration in the 21st century: ten challenges and one reason why they must be met |
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459 | (16) |
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| Index |
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475 | |
Matthias Egger is professor of epidemiology and public health at the University of Bern in Switzerland, as well as professor of clinical epidemiology at the University of Bristol in the United Kingdom.
George Davey-Smith is the editor of Systematic Reviews in Health Care: Meta-Analysis in Context, 2nd Edition, published by Wiley.
Douglas G. Altman, Centre for Statistics in Medicine, University of Oxford and EQUATOR Network, Oxford, UK.
Lisainfo e-raamatute kohta