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E-raamat: Systems Biology

  • Formaat: PDF+DRM
  • Sari: Methods in Molecular Biology 2745
  • Ilmumisaeg: 07-Dec-2023
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071635773
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  • Formaat: PDF+DRM
  • Sari: Methods in Molecular Biology 2745
  • Ilmumisaeg: 07-Dec-2023
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071635773

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This second edition volume expands on the previous edition with discussions of the latest advancements and methods used by scientists to study systems biology. The chapters in this book are organized into four parts. Part One looks at models in systems biology and parameters identification such as short peptide analysis, metastasis models, and metabolomics. Part Two covers computational methods in the study of organisms, and cancer non-linear dynamics. Part Three discusses critical transition states across Waddington’s like landscapes such as understanding cell differentiation through single-cell approaches and modeling mammary organogenesis from biological first principles. Part Four talks about specific fields of investigation including inborn errors of metabolism, system biology approach in epithelial-mesenchymal transition, and an approach to understanding how COVID-19 spreads in the population. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and comprehensive, Systems Biology, Second Edition is a valuable tool for any researcher looking to learn more about this important and developing field.

Identifying Key In Silico Knockout for Enhancement of Limonene Yield
through Dynamic Metabolic Modelling.- The Search for Systems Parameters: A
Statistical and Dynamical Description from Complex Network
Analysis.- Untargeted Analysis of Short-Chain Peptides in Urine Samples Short
Peptides Analysis.- Metastasis Models: Thermodynamics and
Complexity.- Metabolomics: Challenges and Opportunities in Systems Biology
Studies.- Optical Estimation of Bioelectric Patterns in Living
Embryos.- Mathematical Modeling in the Study of Organisms and Their
Parts.- Systems Biology Modelling of Cancer Non-Linear Dynamics.- From Cell
States to Cell Fates: Control of Cell State Transitions.- Understanding Cell
Differentiation through Single-Cell Approaches: Conceptual Challenges of the
Systemic Approach.- Modelling Mammary Organogenesis from Biological First
Principles: A Systems Biology Approach.- Systems Biology and Inborn Error of
Metabolism: Analytical Strategy in Investigating Different
Biochemical/Genetic Parameters.- Systems Biology Approach in Investigating
Epithelial-Mesenchymal Transition (EMT).- An Enhanced Quantitative Reverse
Transcription-PCR Approach for Measuring Circulating MicroRNAs.- Systems
Biology Approaches to Understanding COVID-19 Spread in the Population.