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E-raamat: Technical Evaluation of the NASA Model for Cancer Risk to Astronauts Due to Space Radiation

  • Formaat: 86 pages
  • Ilmumisaeg: 19-Mar-2012
  • Kirjastus: National Academies Press
  • Keel: eng
  • ISBN-13: 9780309253086
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  • Formaat: 86 pages
  • Ilmumisaeg: 19-Mar-2012
  • Kirjastus: National Academies Press
  • Keel: eng
  • ISBN-13: 9780309253086

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NASA's current missions to the International Space Station (ISS) and potential future exploration missions involving extended stays by astronauts on the lunar surface, as well as the possibility of near- Earth object (NEO) or Mars missions, present challenges in protecting astronauts from radiation risks. These risks arise from a number of sources, including solar particle events (SPEs), galactic cosmic rays (GCRs), secondary radiation from surface impacts, and even the nuclear isotope power sources transported with the astronauts. The serious early and late radiation health effects potentially posed by these exposures are equally varied, ranging from early signs of radiation sickness to cancer induction. Other possible effects include central nervous system damage, cataracts, cardiovascular damage, heritable effects, impaired wound healing, and infertility. Recent research, much of which has been sponsored by NASA, has focused on understanding and quantifying the radiation health risks posed by space radiation environments. Although many aspects of the space radiation environments are now relatively well characterized, important uncertainties still exist regarding biological effects and thus regarding the level and types of risks faced by astronauts. This report presents an evaluation of NASA's proposed space radiation cancer risk assessment model, which is described in the 2011 NASA report, Space Radiation Cancer Risk Projections and Uncertainties--2010. The evaluation in Technical Evaluation of the NASA Model for Cancer Risk to Astronauts Due to Space Radiation considers the model components, input data (for the radiation types, estimated doses, and epidemiology), and the associated uncertainties. This report also identifies gaps in NASA's current research strategy for reducing the uncertainties in cancer induction risks.
SUMMARY
1(54)
1 Introduction
9(6)
General Cancer Risk Estimation Approach
9(1)
Evaluating the NASA Model
10(3)
Updating of the Current Model
10(1)
NASA's Proposed Model
11(2)
Approach to the Committee's Evaluation
13(1)
References
13(2)
2 Review of NASA Model
15(40)
Introduction
15(1)
Space Radiation Environments and Transport Models
15(9)
Galactic Cosmic Rays
16(3)
Solar Particle Events
19(4)
Transport Model
23(1)
Final Comments
24(1)
Cancer Risk Projection Models
24(4)
Overview
24(1)
Cancer Mortality Risk Estimation
25(1)
Transfer from the Japanese to the U.S. Population
26(1)
Dose and Dose Rate Effectiveness Factor
27(1)
Risk Models for Never-Smokers
27(1)
Additional Minor Issues
28(1)
Uncertainties in Low Linear Energy Transfer Risk Model
28(2)
Overview
28(1)
Epidemiological Basis for Radiation-Related Cancer Risk Estimation
28(1)
Uncertainty-Related Bias
29(1)
Radiation Risk Protection
29(1)
Dependence on Atomic Bomb Survivor Data
29(1)
Miscellaneous Comments
30(1)
Cancer Risks and Radiation Quality in the Model
30(6)
Overview
30(2)
Quality Factors for Leukemia and Solid Cancers
32(1)
Replacement of LET-Based Quality Factors with Track Structure-Based Quality Factors
33(1)
Risk Cross Sections and Quality Factors
34(1)
Non-Targeted Effects in the NASA Model
35(1)
Qualitative Differences Between Low-LET Radiation and Heavy-Ion Biological Effects
35(1)
Data or Research That Could Improve This Portion of NASA's Proposed Model
36(1)
Integration and Completeness of the Model
36(12)
Background
36(3)
Model Completeness, Improvements, and Recommendations
39(9)
References
48(7)
APPENDIXES
A Statement of Task
55(2)
B Committee and Staff Biographical Information
57(6)
C Glossary and Acronyms
63