This unique volume covers specific aspects of the biological chemistry of terpenoids. It provides extensive information related to classification, general methods of extraction and isolation of terpenoids, synthesis and pharmacological activities of monoterpenoids, synthesis and medicinal uses of diterpenoids, biogenesis of terpenoids, synthesis and medicinal uses of sesqui terpenoids and sesterpenoids. Some terpenes are also classified as diterpene alkaloids. Most of the terpenoids with diverse molecular structures are biologically active and are used for the treatment of various diseases such as cancer, malaria, inflammation, tuberculosis and infection, and this is discussed.
Features:
Activities and biological relationships of terpenes An accurate assessment of where and what terpenes can lead to Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes Arranged by biological activities and usage Provides information on eukaryotic enzymes that have been shown to be a source of ethnobotanical terpenes
| Preface |
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vii | |
| Acknowledgement |
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ix | |
| Authors |
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xi | |
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1 Classification, General Methods of Extraction and Isolation of Terpenoids |
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1 | (28) |
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2 Synthesis and Pharmacological Activities of Monoterpenoids |
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29 | (58) |
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3 Synthesis, and Medicinal Uses of Diterpenoids 6 |
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87 | (66) |
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4 Name Reactions in Terpenoid Chemistry |
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153 | (28) |
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5 Biogenesis of Terpenoids |
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181 | (16) |
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6 Anticancer Natural Terpenoids |
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197 | (32) |
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229 | (26) |
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8 Terpenes as Starting Compounds for Other Types of Molecules Including Alkaloids |
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255 | (30) |
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9 Synthesis and Medicinal Uses of Triterpenoids |
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285 | (46) |
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10 Synthesis and Medicinal Uses of Sesquiterpenoids and Sesterpenoids |
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331 | (30) |
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11 Terpenes as Useful Drugs |
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361 | (38) |
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12 Terpenoids: A Brief Survey of Naturally Occurring Terpenes Molecules |
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399 | (54) |
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13 A Brief Account on Plant and Marine-Derived Terpenoids |
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453 | (14) |
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14 A Synthetic Overview of Terpenes and Nor Diterpenes |
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467 | (20) |
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15 Sesquiterpenes: A Chemical Synthesis and Biological Activity |
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487 | (30) |
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16 Sesquiterpenes Lactone: Biogenesis and Chemical Synthesis |
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517 | (30) |
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17 An Overview of Lactarane: A New Class of Bio-Active Molecules |
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547 | (10) |
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18 Terpenes: A Potential Chiral Pool for the Synthesis of Medicinally Privileged Bioactive Molecules |
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557 | (32) |
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19 Terpenes: A Unique Source of Oil and Fragrance in Industry |
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589 | (22) |
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| Index |
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611 | |
Professor Bimal Krishna Banik
Bimal Krishna Banik conducted his Ph. D. degree work in Chemistry at the Indian Association for the Cultivation of Science, Calcutta. Then, he pursued postdoctoral research at Case Western Reserve University, Ohio and Stevens Institute of Technology, New Jersey. Dr. Banik is a FRSC and CChem of the Royal Society of Chemistry, UK. Dr. Banik was a Tenured Full Professor in Chemistry and First Presidents Endowed Professor in Science & Engineering at the University of Texas-Pan American (UTPA). He was also the Vice President of Research & Education Development at the Community Health Systems of Texas. At present, he is a Full Professor and Senior Researcher of Natural Sciences & Human Studies at Prince Mohammad Bin Fahd University, Kingdom of Saudi Arabia.
Professor Banik has been conducting synthetic chemistry and medicinal research on diverse cancers, antibiotics, hormones, carbohydrates, metals and salts, natural products, catalysis and environmentally benign methods. As the Principal Investigator, he has been awarded $7.25 million grants from US NIH, US NCI and US Private Foundations. At present, he has 578 publications, 513 presentation abstracts and 8017 journal citations with 47 h-index. Due to his contributions to research, Professor Banik is designated as a "Distinguished Researcher" and a "Distinguished Scientist" by Scientific Organizations.
Professor Biswa Mohan Sahoo
Dr. Biswa Mohan Sahoo is currently working as Professor at Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha. He is also serving as Research Coordinator of Biju Patnaik University of Technology Nodal Centre of Research, Odisha. Dr. Sahoo obtained his B. Pharm. Degree from Berhampur University, Odisha, and a Master's degree from the Department of Medicinal Chemistry, L.M College of Pharmacy, Gujarat.
Dr. Sahoo has received his Ph.D. degree from the School of Pharmaceutical Education and Research, Berhampur University. He has also completed his Post Graduate Diploma in Pharmaceutical Regulatory Affairs from Dept. of Pharmaceutics, Hamdard University, New Delhi. He has published more than 60 research and review articles in peer-reviewed national and international journals of repute. His h-index is 11.
He has filed and published 4 patents in India and Australia and authored several book chapters in various textbooks published by known authors. He is an editorial board and advisory board member of various international journals. He is recognized as a Ph.D. Supervisor under Jawaharlal Nehru Technological University (JNTU) Kakinada, Mewar University, Rajsthan and BPUT, Odisha.
Professor Abhishek Tiwari
Dr. Abhishek Tiwari is working as Professor, Department of Pharmaceutical Chemistry, IFTM University, Lodhipur-Rajput, Moradabad (U. P.) India. Dr Tiwari has received more than 15 lakhs grant from Department of Biotechnology, Uttarakhand, All India Council of Technical Education, India, Oil and Natural Gas corporation and Power Finance Corporation. Dr. Tiwari has granted one Indian and four Australian patents. In addition, he has submitted a number of patents for approval.
Dr. Tiwari is a nominee of Committee for the purpose and Supervision of Experiments in Animals and editorial member of various national and international journals. He has received "Best Author Award" from Nirali Prakashan, Pune, 2019 and "Best Teacher Award" from SPER in 2019, "Outstanding Teacher Award" from management of Devtshali Vidyapeeth in 2014 & 2015. He has published many research papers in International journals. Remarkably, he has published more than 17 Indian books and a few chapters. He has been supervising numerous doctorate and masters students.
Lisainfo e-raamatute kohta