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E-raamat: Textbook of Organ Transplantation Set

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  • Ilmumisaeg: 21-Jul-2014
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  • ISBN-13: 9781118889633
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  • Formaat: EPUB+DRM
  • Ilmumisaeg: 21-Jul-2014
  • Kirjastus: Wiley-Blackwell
  • Keel: eng
  • ISBN-13: 9781118889633
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A mammoth project, this two-volume set covers a complex field involving extensive management and coordination, policy considerations, and navigation of the difficulties of immune response. This reference is not intended to replace primary, in-depth literature on each of the topics covered but rather to serve as a starting point. Regular updates are planned including links (in the electronic version) to the in-depth sources. Material is arranged to correspond with the chronology of a clinician's work. The basics of immunology, experimental transplantation, and mechanisms of immune modulation are covered first. Following is coverage of organ procurement, pre-operative management (including waiting list management), transplant procedure and surgical technique, post-transplant management, long-term outcomes, pediatric patients, transplant administration, clinical trials and data management, and transplant policy. Annotation ©2014 Ringgold, Inc., Portland, OR (protoview.com)

Provides an overview of modern transplantation in all its complexity, from basic science to gold-standard surgical techniques to post-operative care, and from likely outcomes to considerations for transplant program administration, bioethics and health policy.

Brought to you by the world’s leading transplant clinicians, Textbook of Organ Transplantation providesa complete and comprehensive overview of modern transplantation in all its complexity, from basic science to gold-standard surgical techniques to post-operative care, and from likely outcomes to considerations for transplant program administration, bioethics and health policy.

Beautifully produced in full color throughout, and with over 600 high-quality illustrations, it successfully:

  • Provides a solid overview of what transplant clinicians/surgeons do, and with topics presented in an order that a clinician will encounter them.
  • Presents a holistic look at transplantation, foregrounding the interrelationships between transplant team members and non-surgical clinicians in the subspecialties relevant to pre- and post-operative patient care, such as gastroenterology, nephrology, and cardiology.
  • Offers a focused look at pediatric transplantation, and identifies the ways in which it significantly differs from transplantation in adults.
  • Includes coverage of essential non-clinical topics such as transplant program management and administration; research design and data collection; transplant policy and bioethical issues.

Textbook of Organ Transplantationis the market-leading and definitive transplantation reference work, and essential reading for all transplant surgeons, transplant clinicians, program administrators, basic and clinical investigators and any other members of the transplantation team responsible for the clinical management or scientific study of transplant patients.

List of Contributors
xi
Volume 1
Section 1 History/Introduction
1(12)
Introduction
3(2)
Allan D. Kirk
1 A Brief History of Clinical Organ Transplantation
5(8)
Sir Roy Y. Calne
Section 2 Transplantation Biology
13(238)
Immunology
2 An Overview of Physiologic Immunity
15(15)
Heth R. Turnquist
Giorgio Raimondi
Diana Metes
Angus W. Thomson
3 Transplant Antigens: A Brief History of HLA
30(6)
Paul I. Terasaki
4 Transplant Antigen Biology
36(14)
Raja Rajalingam
Qiuheng Zhang
J. Michael Cecka
Elaine F. Reed
5 Cellular Mechanisms of Adaptive Immunity
50(10)
Maria-Luisa Alegre
6 Humoral Mechanisms of Adaptive Immunity
60(8)
William M. Baldwin
Robert L. Fairchild
7 Innate Immunity
68(11)
Melissa Y. Yeung
Sacha A. De Serres
Xian C. Li
8 Mechanisms of Immune Regulation
79(8)
Kathryn J. Wood
Andrew Bushell
Joanna Hester
9 The Spectrum of Alloimmunity, Heterologous Immunity, and Relevant Autoimmunity
87(12)
Mandy L. Ford
Andrew B. Adams
Christian P. Larsen
10 Fundamental Concepts Regarding Graft Injury and Regeneration: Tissue Injury, Tissue Quality, and Recipient Factors
99(20)
Chatchai Kreepala
Konrad S. Famulski
Philip F. Halloran
11 Mechanisms of Allograft Tolerance
119(15)
Raul Badell
Allan D. Kirk
12 Xenoimmunity
134(16)
Peter J. Cowan
Anthony J.F. d'Apice
Experimental Transplantation
13 In Vitro Models of Alloreactivity
150(8)
Charles A. Su
Anna Valujskikh
William M. Baldwin
Robert L. Fairchild
14 Small Animal Models of Transplantation
158(27)
Lakshman Gunaratnam
Anthony M. Jevnikar
Roslyn B. Mannon
15 Large Animal Models of Transplantation
185(23)
Douglas J. Anderson
Benjamin M. Martin
Allan D. Kirk
David H. Sachs
16 Advancing Transplantation In Silico: Studying Global Gene Expression Using Functional Genomics for Transplantation Research
208(11)
Steven Head
Sunil M. Kurian
Daniel R. Salomon
Mechanisms of Immune Modulation
17 Current Pathways for Immune Manipulation
219(20)
Jason R. Lees
Agnes M. Azimzadeh
Yaozhong Ding
Jiangnan Xu
Jonathan S. Bromberg
18 Future Pathways for Immune Manipulation
239(12)
Allison B. Webber
Flavio Vincenti
Section 3 Organ Procurement
251(100)
Organ Procurement and Allocation
19 Administration of Organ Procurement and Allocation
253(11)
Jennifer M. Porter
Lori E. Brigham
Susan Gunderson
20 Deceased Donor Management
264(13)
John Fung Koji Hashimoto
Bijan Eghtesad
Daniel J. Lebovitz
Melissa Watson
Techniques for Organ Procurement
21 Techniques for Organ Procurement after Brain Death
277(11)
Rupert Oberhuber
Timm Heinbokel
Zain Khalpey
Sayeed Malek
Stefan G. Tullius
22 Techniques for Organ Procurement after Circulatory Death
288(5)
Chandrasekar Santhanakrishnan
Anthony M. D'Alessandro
23 Techniques for Living Donor Kidney Procurement
293(16)
Andrew B. Adams
Ashtar Chami
Kenneth A. Newell
24 Techniques for Living Donor Liver Procurement
309(10)
Koji Hashimoto
Cristiano Quintini
Charles M. Miller
Organ Preservation and Resuscitation
25 Abdominal Organ Preservation and Resuscitation
319(15)
Henri G.D. Leuvenink
Rutger J. Ploeg
26 Thoracic Organ Preservation and Resuscitation
334(9)
Jonathan C. Yeung
Marcelo Cypel
John M. Craig
Shaf Keshavjee
27 Kidney Paired Donation Networks
343(8)
Adam W. Bingaman
Cathi L. Murphey
Section 4 Pre-operative Management of Transplant Patients
351(266)
Patient Selection and Indications for Organ Transplantation
28 Patient Selection and Indications for Kidney Transplantation
353(11)
Jeremy Goodman
Robert S. Gaston
29 Patient Selection and Indications for Liver Transplantation
364(13)
Kimberly A. Brown
Marwan Kazimi
30 Patient Selection and Indications for Heart Transplantation
377(11)
Andrew L. Smith
Daniel B. Sims
31 Patient Selection and Indications for Lung Transplantation
388(16)
Julia B. Becker
Edward R. Garrity Jr.
32 Patient Selection and Indications for Pancreas and Islet Transplantation
404(8)
Alexandra Turner
Nicole A. Turgeon
33 Patient Selection and Indications for Intestinal and Multivisceral Organ Transplantation
412(4)
Douglas G. Farmer
Robert S. Venick
34 Role of Primary Care Provider in the Referral and Care of Abdominal Organ Transplant Patients
416(12)
Peggy B. Hasley
Kristine S. Schonder
Ron Shapiro
35 Role of Primary Care Provider in the Referral and Care of Thoracic Organ Transplant Patients
428(15)
Remzi Bag
Arvind Bhimaraj
Sireesha Garikipati
The Histocompatibility Lab
36 Alloantibodies, Sensitization and Virtual Crossmatching
443(9)
Howard M. Gebel
Robert A. Bray
Waiting List Management
37 Waiting List Management for Kidney Transplantation
452(10)
Phuong-Thu T. Pham
Phuong-Chi T. Pham
Gabriel M. Danovitch
38 Waiting List Management for Liver Transplantation
462(8)
John G. O'Grady
39 Waiting List Management for Heart Transplantation
470(6)
Howard J. Eisen
40 Waiting List Management for Lung Transplantation
476(6)
E. Clinton Lawrence
David C. Neujahr
41 Waiting List Management for Pancreas and Islet Transplantation
482(7)
Jon S. Odorico
42 Waiting List Management for Intestinal and Multivisceral Transplantation
489(6)
Kareem M. Abu-Elmagd
Guilherme Costa
Intensive Care in End Organ Failure
43 Intensive Care in Hepatic Failure
495(8)
Jenny E. Han
Ram M. Subramanian
44 Intensive Care in Cardiac Failure
503(17)
Josef Stehlik
Michael S. Kiernan
Deborah Budge
Maryl R. Johnson
45 Intensive Care in Pulmonary Failure
520(10)
John Adam Reich
Richard Eliot Fagley
Artificial Organs and Assist Devices
46 Dialysis
530(15)
Myriam Farah
John S. Gill
47 The Artificial Liver, in vivo Tissue Engineering, and Organ Printing
545(9)
Igor M. Sauer
Nathanael Raschzok
Peter Neuhaus
48 Ventricular Assist Devices
554(9)
O.H. Frazier
Steven M. Parnis
49 The Artificial Heart
563(5)
Hannah Copeland
Jennifer Berumen
Richard G. Smith
Jack G. Copeland
50 Artificial Lungs
568(8)
Claire A. Watkins
Bartley P. Griffith
51 The Artificial Pancreas
576(8)
Desmond Barry Keenan
Garry M. Steil
52 Tissue and Organ Bioengineering
584(10)
Tracy C. Grikscheit
Erik R. Barthel
Organ Acceptance and Risk Management Assessment
53 Organ Assessment and Acceptance for Standard and Expanded Criteria Donors
594(11)
Matthew Cooper
Stephen T. Bartlett
54 Organ Assessment and Acceptance for Donation after Circulatory Death Donors
605(12)
Silke Niederhaus
Anthony M. D'Alessandro
Section 5 Transplant Procedure and Surgical Technique
617(98)
55 Kidney Transplantation Procedure and Surgical Technique
619(12)
Paul L. Tso
Thomas C. Pearson
56 Liver Transplantation Procedure and Surgical Technique
631(8)
Joseph F. Magliocca
Steven I. Hanish
Eugenia K. Page
Stuart J. Knechtle
57 Living Donor Liver Transplantation Procedure and Surgical Technique
639(18)
Sung-Gyu Lee
Deok-Bog Moon
Jung-Man Namgoong
58 Heart Transplantation Procedure and Surgical Technique
657(10)
John M. Craig
Soyoung Lee
Gus J. Vlahakes
Joren C. Madsen
59 Lung Transplantation Procedure and Surgical Technique
667(7)
R. Duane Davis
Matt Hartwig
60 Pancreas Transplantation Procedure and Surgical Technique
674(8)
Dixon B. Kaufman
Jon Odorico
Hans W. Sollinger
61 Islet Cell Transplantation Procedure and Surgical Technique
682(9)
A.M. James Shapiro
Gamillo Ricordi
62 Intestinal Transplantation Procedure and Surgical Technique
691(6)
Thomas Fishbein
63 Multivisceral Transplantation Procedure and Surgical Technique
697(6)
Lokesh Bathla
Alan Langnas
64 Vascularized Composite Allograft Transplantation Procedure and Surgical Technique
703(12)
Gerald Brandacher
Jaimie T. Shores
Chad R. Gordon
Damon S. Cooney
W.P. Andrew Lee
Index
Volume 2
Section 6 Post-transplant Management
715(542)
Immunosuppressive Therapy
65 Induction Immunosuppressive therapy
717(15)
Alt H. Charafeddine
Allan D. Kirk
66 Maintenance Immunosuppressive Therapy
732(22)
Karen L. Hardinger
Daniel C. Brennan
Christina L.M. Klein
67 Rescue Immunosuppressive Therapy
754(9)
Mark D. Stegall
Patrick G. Dean
68 Desensitization Protocols for Organ Transplantation
763(10)
Carmen Lefaucheur
Denis Glotz
Clinical Allograft Rejection Syndromes: Diagnosis and Management
69 Clinical Allograft Rejection Syndromes in Kidney Transplantation
773(16)
Brian J. Nankivell
70 Clinical Allograft Rejection Syndromes in Liver Transplantation
789(13)
Matthew H. Levine
Sandy Feng
71 Clinical Allograft Rejection Syndromes in Heart Transplantation
802(11)
Keyur B. Shah
Joren C. Madsen
Mandeep R. Mehra
72 Clinical Allograft Rejection Syndromes in Lung Transplantation
813(11)
David C. Neujahr
73 Clinical Allograft Rejection Syndromes in Pancreas and Islet Transplantation
824(6)
Parsia A. Vagefi
Peter G. Stock
74 Clinical Allograft Rejection Syndromes in Intestinal Transplantation
830(5)
Andreas Tzakis
Gennaro Selvaggi
Akin Tekin
Jennifer Garcia
Ji Fan
Phil Ruiz Jr.
75 Clinical Allograft Rejection Syndromes in Vascularized Composite Allotransplantation
835(9)
Stefan Schneeberger
Gerald Brandacher
76 Clinical Transplantation Tolerance
844(11)
Tatsuo Kawai
David H. Sachs
A. Benedict Cosimi
Clinical Recurrent Disease: Diagnosis and Management
77 Recurrent Disease after Kidney and Pancreas Transplantation
855(14)
Lorna K. Henderson
Philip J. O'Connell
78 Recurrent Disease after Liver Transplantation
869(14)
Samir Parekh
James R. Spivey
79 Recurrent Disease after Heart Transplantation
883(15)
Jignesh K. Patel
Jon A. Kobashigawa
80 Recurrent Disease after Lung Transplantation
898(12)
Todd L. Astor
Histopathological Syndromes of Graft Rejection and Recurrent Disease
81 Histopathological Syndromes of Kidney Allograft Rejection and Recurrent Disease
910(17)
Alton Brad Farris
Michael H. Mengel
82 Histopathological Syndromes of Liver Allograft Rejection and Recurrent Disease
927(30)
Anthony J. Demetris
Marta I. Minervini
Michael A. Nalesnik
Erin Rubin
Parmjeet Randhawa
Eizaburo Sasatomi
83 Histopathological Syndromes of Heart Allograft Rejection and Recurrent Disease
957(24)
E. Rene Rodriguez
Carmela D. Tan
84 Histopathological Syndromes of Lung Allograft Rejection and Recurrent Disease
981(8)
Carol Farver
W. Dean Wallace
85 Histopathological Syndromes of Pancreas and Islet Allograft Rejection and Recurrent Disease
989(22)
Cinthia Beskow Drachenberg
John C. Papadimitriou
86 Histopathological Syndromes of Intestinal Allograft Rejection and Recurrent Disease
1011(12)
Phillip Ruiz
Jennifer Garcia
Akin Tekin
Seigo Nishida
Andreas Tzakis
87 Histopathological Syndromes of Vascularized Composite Allograft Rejection and Recurrent Disease
Alexandra P. Turner
Alton Brad Farris
Alessandrina M. Freitas
Linda C. Cendales
Post-operative Monitoring
1023(7)
88 Cardiovascular Disease and Preventive Healthcare after Organ Transplantation
1030(29)
Stephen Pastan
Divya Gupta
89 Monitoring for HLA Antibody after Organ Transplantation
1059(6)
Robert A. Bray
Howard M. Gebel
90 Biomarkers and Alloimmune Monitoring after Organ Transplantation
1065(14)
Oriol Bestard
Birgit Sawitzki
Alberto Sanchez-Fueyo
91 Protective Immune Competence after Organ Transplantation
1079(9)
Aneesh K. Mehta
Transplant Infectious Diseases
92 Donor-derived Infections after Organ Transplantation
1088(17)
Marissa B. Wilck
Emily A. Blumberg
93 Perioperative Infections after Organ Transplantation
1105(12)
Daniel Kaul
Michael Green
94 Late Infectious Disease after Organ Transplantation
1117(17)
Jay A. Fishman
Robin K. Avery
Malignancy in Transplantation
95 General Malignancy after Organ Transplantation
1134(13)
Oriol Bestard
Josep M. Cruzado
Josep M. Grinyo
96 Post-Transplant Lymphoproliferative Disorders
1147(14)
Michael Green
Steven A. Webber
Pregnancy and Contraception in Transplantation
97 Pregnancy and Contraception in Transplantation
1161(18)
Serban Constantinescu
Veronica Gomez-Lobo
John M. Davison
Michael J. Moritz
Vincent T. Armenti
The Transplant Pharmacopeia
98 Drugs Specifically Approved for Transplant Indications
1179(23)
Winston A. Ally
Avinash Agarwal
99 Infectious Disease Prophylaxis after Organ Transplantation
1202(11)
G. Marshall Lyon
100 Metabolic and Endocrine Management of the Organ Transplant Recipient
1213(20)
Naim Issa
Scott A. Reule
Aleksandra Kukla
101 Off-Label Use of Immunosuppressive Agents in Solid Organ Transplantation
1233(9)
Jill C. Krisl
Rita R. Alloway
E. Steve Woodle
102 Drug Interactions in Organ Transplantation
1242(15)
William D. Simmons
Pamala A. Jacobson
Karen L. Hardinger
Section 7 Long-term Transplant Outcomes
1257(96)
103 Long-term Outcomes after Kidney Transplantation
1259(8)
Sundus A. Lodhi
Neema Stephens
104 Long-term Outcomes after Liver Transplantation
1267(13)
Heidi Yeh
Paulo Martins
James F. Markmann
105 Long-term Outcomes after Heart Transplantation
1280(8)
Michelle M. Kittleson
Jon A. Kobashigawa
106 Long-term Outcomes after Lung and Heart-Lung Transplantation
1288(12)
Toshihiro Okamoto
David Wheeler
Kenneth R. McCurry
107 Long-term Outcomes after Pancreas Transplantation
1300(14)
Philip Y. Wai
Hans W. Sollinger
108 Long-term Outcomes after Islet Transplantation
1314(20)
A.M. James Shapiro
Camillo Ricordi
109 Long-term Outcomes after Intestinal and Multi-visceral Transplantation
1334(4)
Jennifer Garcia
Gennaro Selvaggi
Akin Tekin
Phillip Ruiz
Andreas Tzakis
110 Long-term Outcomes after Vascularized Composite Allograft Transplantation
1338(15)
Alessandrina M. Freitas
Linda C. Cendales
Section 8 Pediatric Transplant
1353(136)
111 An Introduction to Pediatric Organ Transplantation
1355(2)
Steven A. Webber
Allan D. Kirk
112 Developmental Immunity: From Birth to Adult
1357(13)
Simon Urschel
Lori J. West
113 Pediatric Kidney Transplantation
1370(20)
William Harmon
114 Pediatric Liver Transplantation
1390(16)
John C. Bucuvalas
Sandy Feng
115 Pediatric Heart Transplantation
1406(14)
Steven A. Webber
116 Pediatric Lung Transplantation
1420(1)
Albert Faro
Stuart C. Sweet
117 Pediatric Intestinal and Multivisceral Organ Transplantation
1420(15)
Douglas G. Farmer
Special Pediatric Considerations
118 Growth and Development after Organ Transplantation
1435(8)
Franz Schaefer
119 Cognitive Development and Functional Outcomes after Organ Transplantation
1443(10)
Estella M. Alonso
Saeed Mohammad
Lisa G. Sorensen
120 Nonadherence, Psychosocial Adaptation and Its Effects in Pediatric Transplantation
1453(22)
Robert Ettenger
Margaret L. Stuber
121 Management of the Organ Transplant Recipient in the Transition from Pediatric to Adult Care
1475(14)
Sandra Amaral
Lorraine E. Bell
Section 9 Transplant Administration
1489(92)
122 Transplant Coordination
1491(6)
Dianne LaPointe Rudow
123 Transplant Pharmacy Services
1497(12)
Christin C. Rogers
Nicole A. Pilch
Eric M. Tichy
Lonnie D. Smith
David J. Taber
Rita R. Alloway
124 Inpatient Transplant Unit Management
1509(9)
Linda Ohler
Margaret Schaeffer
Kelly Carter
Donna George
125 Transplant Clinic Management
1518(15)
Elizabeth A. Kallenborn
Chris Shay-Downer
Kathy Schwab
Shelley Zomak
126 Transplant Center Management and Leadership -- A Case for Structured Intrapreneurship
1533(9)
Luke Preczewski
Gwen McNatt
Michael Abecassis
127 Transplant Quality Programs
1542(7)
Christian Morath
Peter Schemmer
Martin G. Zeier
128 National and International Transplant Management and Oversight
1549(13)
Virginia A. McBride
Esther-Marie Carmichael
Linda Ohler
Jeremy Chapman
Transplant Education
129 Abdominal Solid Organ Transplantation Fellowship Training
1562(4)
Rachel C. Forbes
Mitchell L. Henry
130 Medical Solid Organ Transplant Fellowship Training
1566(6)
Deirdre Sawinski
Roy D. Bloom
131 Transplantation in General Medical Education
1572(9)
Rowena Delos Santos
Douglas J. Norman
Section 10 Clinical Trials and Data Management
1581(58)
132 Building and Sustaining a Local Transplant Data Management Program
1583(15)
Regina Eady
Tim Morris
Marc J. Overcash
Jeff Weaver
133 National Transplant Data Registries and Population Studies
1598(9)
Allan B. Massie
Dorry L. Segev
134 Clinical Research Methods and Analysis in Organ Transplantation
1607(15)
Jesse D. Schold
S. Joseph Kim
135 Comparative Effectiveness in Transplantation
1622(17)
Edward A. Meister
Bruce Kaplan
Section 11 Transplant Policy
1639
Transplant Ethics
136 Transplant Ethics for Clinicians
1641(4)
Richard N. Formica Jr.
Francis L. Delmonico
137 The Ethics of Organ Allocation
1645(9)
Richard S. Luskin
Alexandra K. Glazier
138 The Ethics of Living Donation
1654(8)
Alice Peng
Andrew Klein
139 Cultural Variations in Organ Transplantation
1662(11)
Chris J. Callaghan
J. Andrew Bradley
Economic and Societal Impact of Transplantation and Transplant Policy
140 Federal and Private Insurance Coverage for Organ Transplantation
1673(6)
Timothy L. Pruett
141 Drug Development in Solid Organ Transplantation and the Approval Process for Transplant Immunosuppressants
1679(11)
Candace Wang
J. Mark Hexham
Alan Slade
Peter Heining
Ronald G. Van Valen
Guido Junge
Marc I. Lorber
142 Organ Specific Benefits of Transplantation: Outcomes and Economics
1690(13)
David A. Axelrod
Mark Schnitzler
Richard Freeman
143 National Healthcare Policy, Transplant-specific Statutes, and the Future of Organ Transplantation
1703
Keren Ladin
Rui Wang
Douglas W. Hanto
Index
Allan D. Kirk is a Professor of Surgery and Pediatrics and a practicing transplant surgeon and physician at Emory University Hospital and Children's Healthcare of Atlanta. Dr. Kirk was the inaugural Chief of the NIH intramural Transplantation Branch and he has been Principal Investigator (PI) for multiple past and ongoing clinical trials. Dr. Kirk's bibliography contains over 200 peer-reviewed manuscripts and he is Editor-in-Chief of the American Journal of Transplantation.

Joren C. Madsen is the founding Director of the MGH Transplant Center, which encompasses kidney, liver, lung, heart, pancreas and small bowel transplantation and is Co-Director of the Transplantation Biology Research Center, a multi-disciplinary group of scientists translating discoveries in basic immunology into clinical protocols. Dr. Madsen has authored more than 150 publications and served on the editorial boards of Transplantation, the American Journal of Transplantation, and the Annals of Thoracic Surgery. In 2009, Dr. Madsen became the first surgeon to be elected president of the American Society of Transplantation.

Chris Larsen, MD, DPhil, became Dean of Emory University School of Medicine, Vice President for Health Center Integration for the Woodruff Health Sciences Center, and Chairman of the Board of The Emory Clinic in January 2013. An internationally recognized leader in transplant surgery and immunology, Larsen joined the Emory medical faculty in 1991 and was appointed Chair of Surgery in 2009. He became founding director of the Emory Transplant Center (ETC) in 2001, building and directing one of the foremost research and clinical transplantation programs in the world.