"Preface For much of the past century, projection radiography has been the workhorse in the diagnostic imaging clinic. Tomosynthesis, which introduces depth information to the x-ray radiographic image with little or no increase in radiation dose, could potentially replace projection radiography as we move into the twenty-first century. This book, Tomosynthesis Imaging, offers the most comprehensive resource to date for this new emerging imaging technology. Digital tomosynthesis imaging is a novel quasi-three dimensional x-ray imaging modality that has been primarily developed during the past two decades, owing to the availability of large-area digital x-ray detectors. The tomosynthesis image is reconstructed from a sequence of projection images that are acquired from a limited angle x-ray scan, therefore, conceptually, tomosynthesis might be considered as limited-angle CT. Because of the limited angle acquisition, resolution in the reconstructed volume is not isotropic. The resolution in image planes parallel to the detector surface is similar to the native detector resolution, but the resolution perpendicular to the detector surface direction is substantially worse, and depends on the scan arc length and on the size of the detail being imaged. Tomosynthesis imaging is being actively investigated for use in a variety of clinical tasks. Currently, tomosynthesis breast imaging is at the forefront, having received approval for clinical use in Europe and Canada in 2008, and FDA approval in the United States in 2011. Although conventional mammography has been very successful in reducing the breast cancer mortality rate, its sensitivity and specificity are less then desirable, especially for women with dense breast tissue"--Provided by publisher.
An innovative, three-dimensional x-ray imaging technique that enhances projection radiography by adding depth resolution, Tomosynthesis Imaging explores tomosynthesis, an emerging limited-angle tomographic imaging technology that is being considered for use in a range of clinical applications, and is currently being used for breast cancer screening and diagnosis. While conventional mammography has been very successful in reducing breast cancer mortality, it is not perfect. A major limitation of mammography is that the recorded image represents the superposition of complex three-dimensional structures in the breast onto a two-dimensional plane, making detection and diagnosis of breast cancer challenging.
Tomosynthesis produces quasi-three-dimensional images that can significantly enhance the visualization of important diagnostic features. This book highlights the flexibility of tomosynthesis systems for new clinical applications, and provides a detailed discussion of the tomosynthesis acquisition process and the impact of physical factors. It explores such topics as acquisition parameters, system components, modeling, image reconstruction algorithms, and system evaluation.
- Provides in-depth coverage of system design considerations, as well as image reconstruction strategies
- Describes the current state of clinical applications of tomosynthesis, including imaging of the breast and chest, as well as its use in radiotherapy
- Illustrates the merits of tomosynthesis imaging and its potential clinical applications in imaging of the breast and chest, as well as for radiation therapy
Divided into five sections, this text delves into the history and development of tomosynthesis. It introduces tomosynthesis imaging, discusses imaging system design considerations, and reviews image reconstruction algorithms that have been developed for tomosynthesis. It also describes system evaluation methodologies, emphasizes current clinical applications, and examines the future direction for tomosynthesis.
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