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E-raamat: Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications

Edited by (University of Texas at San Antonio, USA), Edited by (University of Texas at San Antonio, USA)
  • Formaat: 275 pages
  • Ilmumisaeg: 06-Jan-2017
  • Kirjastus: CRC Press Inc
  • Keel: eng
  • ISBN-13: 9781315363523
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  • Formaat: 275 pages
  • Ilmumisaeg: 06-Jan-2017
  • Kirjastus: CRC Press Inc
  • Keel: eng
  • ISBN-13: 9781315363523

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Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.
Preface vii
About the Editors ix
Contributors xi
Part I Introduction
1 Bone Grafting Evolution
3(18)
Laura Gaviria
L. Actis
Teja Guda
Joo Ong
Part II Materials for Bone Graft Applications
2 Designing Scaffolds for Bone Tissue Engineering
21(20)
Binulal N. Sathy
Sarita R. Shah
Antonios G. Mikos
Shantikumar V. Nair
3 Ceramic Composites for Bone Graft Applications
41(22)
Joel D. Bumgardner
Carlos M. Wells
Warren O. Haggard
4 Commercial Non-Allograft Bone Graft Products
63(14)
James W. Poser
5 Demineralized Bone Matrix (DBM) and Bone Grafts
77(18)
Su-Gwan Kim
Ji-Su Oh
Part III Biologic Delivery for Bone Grafts
6 Bone Morphogenetic Proteins BMP-2 and BMP-7
95(12)
Junya Sonobe
Kazuhisa Bessho
7 Biologics for Bone Regeneration and Local Delivery Mechanisms
107(20)
Scott A. Guelcher
8 Infection-Related Considerations for Bone Grafts
127(20)
Joseph J. Pearson
Joo Ong
Teja Guda
9 Cell Sources for Orthopedic Defects
147(20)
Christopher R. Rathbone
Marcello Pilia
Jennifer S. McDaniel
Part IV Clinical Considerations
10 Bone Graft and Bone Graft Alternatives in Spine Surgery: From Bench to Bedside
167(22)
Joshua A. Parry
Michael J. Yaszemski
11 Bone Grafts for Craniofacial Applications
189(16)
Sergio A. Montelongo
Teja Guda
Joo Ong
Part V Translational Pathways for Bone Graft Development
12 Preclinical Models: A "Bedside-to-Bench" Directive
205(32)
Larry D. Swain
David L. Games, Jr.
13 Regulatory Premarketing Processes
237(20)
Patsy J. Trisler
Index 257
Joo L. Ong, Teja Guda