The birth of Louise Joy Brown - the world's first baby born following in-vitro fertilization - heralded a medical revolution. Forty years later, many thousands of babies are born each year following IVF. Assisted reproduction is a global industry with a multi-billion dollar turnover. It is a complex mix of science, clinical management, bioethics, and commercial imperatives. Many of the pioneers of IVF are still with us and have a fascinating tale to tell. Here, they relate the story of the development of IVF and related technologies in a way that will prove invaluable to future generations of practitioners seeking to understand the genesis of the specialty. This is not an academic history: rather it takes an informal and anecdotal approach; informing and entertaining for generations of past, present and future medical and scientific specialists of IVF, alongside the millions of parents, who celebrated the successes of IVF treatment worldwide.
With thousands of IVF babies born every year, this science based memoir records the early history and pioneering spirit of in-vitro fertilization. Chapters by internationally-recognized specialists in the field record their personal views on the developments made in their countries; chartering this unique and often controversial field of medicine.
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A stimulating record chartering the history and pioneers of in-vitro fertilization, forty years after the birth of the first baby.
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vii | |
Preface |
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xi | |
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1 A Brief Outline of the History of Human In-Vitro Fertilization |
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1 | (7) |
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2 The Track to Assisted Reproduction: From Animal to Human In-Vitro Fertilization |
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8 | (13) |
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3 The American Roots of In-Vitro Fertilization |
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21 | (7) |
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4 The Story of Patrick Steptoe, Robert Edwards, Jean Purdy, and Bourn Hall Clinic |
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28 | (9) |
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5 Professional Hostility Confronting Edwards, Steptoe, and Purdy in their Pioneering Work on In-Vitro Fertilization |
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37 | (9) |
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6 The Development of In-Vitro Fertilization in Australia |
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46 | (20) |
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7 The Joneses and the Jones Institute |
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66 | (9) |
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8 The Development of In-Vitro Fertilization in North America After the Joneses |
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75 | (9) |
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9 The Brussels Story and the Eureka Moment of Intracytoplasmic Sperm Injection |
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84 | (3) |
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10 The Development of In-Vitro Fertilization in Austria |
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87 | (15) |
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11 The Development of In-Vitro Fertilization in France |
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102 | (2) |
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12 The Development of In-Vitro Fertilization in Italy |
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104 | (7) |
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13 The Development of In-Vitro Fertilization in Scandinavia |
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111 | (9) |
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14 The Development of In-Vitro Fertilization in Spain |
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120 | (5) |
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15 The Development of In-Vitro Fertilization in Greece, Germany, and The Netherlands |
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125 | (7) |
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16 The Development of In-Vitro Fertilization in Israel |
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132 | (9) |
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17 The Development of In-Vitro Fertilization in Latin America |
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141 | (7) |
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Fernando Zegers-Hochschild |
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18 The Development of In-Vitro Fertilization in India |
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148 | (4) |
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19 The Development of In-Vitro Fertilization in China |
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152 | (6) |
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20 The Development of In-Vitro Fertilization in Africa |
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158 | (14) |
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21 The Development of In-Vitro Fertilization in Russia |
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172 | (5) |
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22 The Application of In-Vitro Fertilization in the Management of the Infertile Male |
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177 | (3) |
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23 The Development of Preimplantation Genetic Diagnosis for Monogenic Disease and Chromosome Imbalance |
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180 | (12) |
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24 The Development of Embryo, Oocyte, and Ovarian Tissue Cryopreservation |
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192 | (10) |
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25 The Development of Ovarian Stimulation for In-Vitro Fertilization |
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202 | (6) |
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26 The Development of Microsurgery for Male and Female Infertility |
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208 | (6) |
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27 Embryonic Stem Cells, Medicine's New Frontier |
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214 | (10) |
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28 The Regulation and Legislation of In-Vitro Fertilization |
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224 | (8) |
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29 Research on Assisted Reproduction Families: A Historical Perspective |
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232 | (8) |
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30 The Commercialization of In-Vitro Fertilization |
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240 | (9) |
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Index |
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249 | |
Gabor Kovacs, A.M., is Professor of Obstetrics and Gynaecology, Monash University, Australia. He was a foundation member of the Monash IVF team and International Medical Director of Monash IVF until his retirement in 2015. He is an Honorary Member of International Federation of Fertility Societies (IFFS) and Life Member of The Fertility Society of Australia as well as Family Planning Australia. Peter Brinsden is a Consultant Medical Director of Bourn Hall Clinic. He has Honorary Professorships at the Capital Medical University, Beijing, Peking Union Medical College, and China Southern Medical University, Guangzhou. He served as President of the British Fertility Society from 2009 to 2012. Alan DeCherney has been Director of the Division of Reproductive Endocrinology and Infertility at Yale University, Connecticut, and has chaired the department at Tufts University, Massachusetts, and University of California, Los Angeles. Dr DeCherney has been an Associate Editor of the New England Journal of Medicine and Editor-in-Chief of Fertility and Sterility. He has been president of American Society for Reproductive Medicine (ASRM), Society for Reproductive Investigation (SRI) and Society of Assisted Reproductive Technology (SART). He is a member of the National Academy of Medicine and the Royal College of Obstetrics and Gynaecology.