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PART I Structural and Molecular Bases of Ion Channel Function |
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1 Voltage-Gated Sodium Channels and Electrical Excitability of the Heart |
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1 | (13) |
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2 Voltage-Gated Calcium Channels |
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14 | (17) |
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3 Voltage-Regulated Potassium Channels |
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31 | (10) |
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4 Molecular Regulation of Cardiac Inward Rectifier Potassium Channels |
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41 | (9) |
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5 Mammalian Calcium Pumps in Health and Disease |
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50 | (13) |
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6 Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function |
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63 | (7) |
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7 Organellar Ion Channels and Transporters |
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70 | (15) |
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8 Gap Junctional Connexin43: Novel Insights from the New Millennium and Their Clinical Implications |
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85 | (18) |
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PART II Biophysics of Cardiac Ion Channel Function |
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9 Computational Modeling and Simulation for Human Cardiac Electrophysiology: From Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Adult Cardiomyocytes |
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103 | (10) |
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10 Regulation of Cardiac Calcium Channels |
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113 | (11) |
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11 Molecular Genetics of ATP-Sensitive Potassium Channels in Cardiovascular Diseases |
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124 | (14) |
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12 Role of Enhancers in Transcriptional Regulation of Cardiac Electrical Activity |
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138 | (5) |
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13 Functional Characterization of Ion Channel Gene Variants in Sudden Unexplained Natural Death |
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143 | (12) |
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14 Stretch-Activated Potassium Channels in the Human Heart: Pathophysiologic and Clinical Significance |
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155 | (13) |
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15 Connexins and Pannexins in Cardiovascular Disease |
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168 | (10) |
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16 Excitation-Contraction Coupling |
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178 | (10) |
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PART III Intermolecular Interactions and Cardiomyocyte Electrical Function |
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17 Ion Channel Trafficking in the Heart |
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188 | (22) |
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18 Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5 |
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196 | (14) |
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19 Connecting Cardiac Excitation to the Atomic Interactions of Ion Channels |
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210 | (8) |
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20 Macromolecular Complexes and Cardiac Potassium Channels |
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218 | (10) |
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21 Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias |
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228 | (15) |
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22 The Intercalated Disc: A Molecular Network That Integrates Electrical Coupling, Intercellular Adhesion, and Cell Excitability |
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243 | (15) |
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Chantal J.M. van Opbergen |
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23 Function and Dysfunction of Ion Channel Membrane Trafficking and Posttranslational Modification |
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258 | (8) |
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24 Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling |
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266 | (10) |
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PART IV Cell Biology of Cardiac Impulse Initiation and Propagation |
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25 Coupled Oscillators and Sinoatrial Pacemaker Activity |
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276 | (15) |
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26 Mapping of Cardiac Action Potentials in Zebrafish to Assess Genetic Variants |
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291 | (11) |
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21 Cell-To-Cell Communication and Impulse Propagation |
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302 | (14) |
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28 Mechanisms of Normal and Dysfunctional Sinoatrial Nodal Excitability and Propagation |
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316 | (14) |
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29 Cell Biology of the Specialized Cardiac Conduction System |
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330 | (14) |
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PART V Models of Cardiac Excitation |
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30 Computational Prediction of Drug-Induced Arrhythmias |
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344 | (7) |
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31 Global Optimization Approaches to Generate Dynamically Robust Electrophysiologic Models |
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351 | (11) |
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32 Calcium Signaling in Cardiomyocyte Models With Realistic Geometries |
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362 | (14) |
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33 Theory of Rotors and Arrhythmias |
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376 | (11) |
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34 Distinct ECG Phenotypes Identified in Hypertrophic Cardiomyopathy Using Machine Learning Associated With Arrhythmic Risk Markers |
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387 | (17) |
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35 Computational Approaches for Accurate Rotor Localization in the Atria |
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404 | (14) |
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36 Modeling the Aging Heart |
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418 | (12) |
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37 Electromechanic Imaging of the Heart |
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430 | (14) |
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Johannes Schroder-Schetelig |
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PART VI Neural Control of Cardiac Electrical Activity |
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38 Innervation of the Sinoatrial Node |
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444 | (8) |
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Kristina Rysevaite-Kyguoliene |
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39 Autonomic and Oxidant Regulation of Cardiac Sodium Currents: Mechanisms and Consequences |
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452 | (9) |
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40 Neural Activity and Atrial Tachyarrhythmias |
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461 | (12) |
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41 Sympathetic Modulation of Cardiac Electrophysiology |
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473 | (8) |
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42 Role of the Autonomic Nervous System in Atrial Fibrillation |
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481 | (8) |
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PART VII Arrhythmia Mechanisms |
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43 Rotational and Focal Sources of Atrial Fibrillation: Scientific Rationale and Comparative Clinical Mapping |
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489 | (16) |
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44 Noninvasive Frequency-Phase Mapping of Atrial Fibrillation |
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505 | (8) |
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45 Mechanistic Approaches for Persistent Atrial Fibrillation Ablation |
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513 | (16) |
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46 Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation |
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529 | (17) |
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47 Genetics of Atrial Fibrillation |
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546 | (8) |
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PART VIII Molecular Genetics and Pharmacogenomics |
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48 Mechanisms in Genetic Sodium Channel Diseases |
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554 | (11) |
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49 Genetic, Ionic, and Cellular Mechanisms Underlying the J Wave Syndromes |
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565 | (18) |
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50 Inheritable Potassium Channel Diseases |
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583 | (11) |
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51 Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation |
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594 | (10) |
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PART IX Pharmacologic, Genetic, and Cell Therapy of Ion Channel Dysfunction |
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52 Dominant Frequency as a Tool for Personalized Monitoring of Atrial Fibrillation Progression and Upstream Therapy |
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604 | (11) |
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53 Pharmacogenomics of Cardiac Arrhythmias |
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615 | (7) |
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54 Deep Phenotyping: Adding New Tools to Understand Disease |
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622 | (9) |
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55 Gene Therapy for Atrial Fibrillation |
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631 | (14) |
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PART X Cell Biology and Electrophysiology of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes |
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56 Cardiac Remodeling and Regeneration |
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645 | (9) |
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57 High-Throughput Optical Mapping of Two-Dimensional hiPSC-CM Platforms for Drug Discovery and Cardiotoxicity Testing |
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654 | (17) |
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58 Functional Cardiac Fibroblasts Derived From Human Pluripotent Stem Cells via Second Heart Field Progenitors |
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671 | (9) |
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59 Challenges of Human iPSC-CM Technology: Increasingly Complex Approaches Improve Cell Maturation and Relevance to Modeling Human Cardiac Disease |
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680 | (13) |
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Maria Linarejos Vera Pedrosa |
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PART XI Diagnostic Evaluation |
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60 Assessment of the Patient With a Cardiac Arrhythmia |
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693 | (7) |
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61 Differential Diagnosis of Narrow and Wide Complex Tachycardias |
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700 | (8) |
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62 Electrocardiographic Monitoring: Short- and Long-Term Recording |
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708 | (8) |
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63 Personal Cardiac Monitoring |
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716 | (12) |
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64 Computed Tomography for Electrophysiology |
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728 | (16) |
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Alejandro Jimenez Restrepo |
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65 Magnetic Resonance Imaging for Electrophysiology |
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744 | (12) |
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66 Intracardiac Echocardiography for Electrophysiology |
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756 | (8) |
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67 Autonomic Nervous System Assessment for Syncope and Arrhythmia Risk |
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764 | (9) |
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68 Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates and Ventricular Arrhythmias |
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773 | (13) |
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786 | (6) |
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PART XII Supraventricular Arrhythmias: Diagnosis and Therapy |
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70 Supraventricular Tachycardias: Diagnostic Maneuvers in the Electrophysiology Laboratory |
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792 | (14) |
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806 | (23) |
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72 Atrioventricular Nodal Reentrant Tachycardia |
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829 | (24) |
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73 Junctional Tachycardia |
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853 | (8) |
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74 Preexcitation, Atrioventricular Reentry, Variants |
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861 | (15) |
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75 Atrial Fibrillation: Mechanisms, Clinical Features, and Management |
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876 | (15) |
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76 Ablation for Atrial Fibrillation |
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891 | (11) |
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77 Left Atrial Appendage Management: Anatomy, Physiology, and Role in Atrial Fibrillation---Related Stroke |
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902 | (9) |
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78 Typical and Atypical Atrial Flutter: Mapping and Ablation |
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911 | (14) |
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PART XIII Ventricular Arrhythmias |
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79 Sudden Cardiac Death in Adults |
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925 | (13) |
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80 Premature Ventricular Complexes |
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938 | (9) |
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81 Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management |
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947 | (13) |
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82 Premature Ventricular Contraction Ablation With Anatomic Guidance: Papillary Muscles, Moderator Band, and Valve Annulus Sites |
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960 | (10) |
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83 Fascicular Ventricular Arrhythmias |
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970 | (7) |
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84 Bundle Branch Reentry Tachycardia |
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977 | (15) |
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85 Ischemic Heart Disease |
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992 | (9) |
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86 Ablation of Postmyocardial Infarction Ventricular Tachycardia |
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1001 | (13) |
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87 Ventricular Tachycardia in Patients With Dilated Cardiomyopathy |
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1014 | (14) |
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88 Lamin A/C, Noncompaction, and Other Genetic Cardiomyopathies With Ventricular Arrhythmias |
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1028 | (10) |
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89 Ventricular Tachyarrhythmias in Hypertrophic Cardiomyopathy: Sudden Death, Risk Stratification, and Prevention With Implantable Defibrillators |
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1038 | (12) |
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90 Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy |
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1050 | (11) |
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91 Catecholaminergic Polymorphic Ventricular Tachycardia |
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1061 | (12) |
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92 Arrhythmias and Conduction Disturbances in Noncompaction Cardiomyopathy |
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1073 | (10) |
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93 Ventricular Arrhythmias in Takotsubo Cardiomyopathy |
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1083 | (6) |
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94 Mitral Valve Prolapse, Ventricular Arrhythmias, and Sudden Death |
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1089 | (11) |
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1100 | (11) |
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96 Long and Short QT Syndromes |
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1111 | (18) |
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97 Andersen-Tawil Syndrome |
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1129 | (7) |
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1136 | (10) |
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1146 | (11) |
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100 Idiopathic and Short-Coupled Ventricular Fibrillation |
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1157 | (9) |
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101 Mapping and Ablation of Ventricular Fibrillation |
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1166 | (12) |
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102 Drug-Induced Ventricular Arrhythmias |
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1178 | (11) |
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PART XIV Syncope and Bradyarrhythmias |
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1189 | (8) |
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104 Sinus Node Abnormalities |
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1197 | (6) |
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105 Postural Orthostatic Tachycardia Syndrome |
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1203 | (6) |
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106 Atrioventricular Block |
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1209 | (9) |
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PART XV Arrhythmias in Special Populations |
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107 Sex Differences in Arrhythmias |
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1218 | (8) |
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108 Sudden Cardiac Deaths in Athletes, Including Commotio Cordis |
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1226 | (14) |
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1240 | (8) |
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110 Sleep-Disordered Breathing and Arrhythmias |
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1248 | (9) |
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111 Ventricular Assist Devices and Cardiac Transplant Recipients |
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1257 | (12) |
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112 Arrhythmia in Neurologic Disease |
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1269 | (17) |
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113 Cancer Therapy-Related Arrhythmias |
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1286 | (10) |
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PART XVI Congenital Heart Disease and Pediatrics |
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114 Arrhythmias in the Pediatric Population |
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1296 | (18) |
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115 Supraventricular Tachycardias in Congenital Heart Disease |
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1314 | (16) |
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116 Ventricular Arrhythmias in Congenital Heart Disease |
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1330 | (17) |
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PART XVII Pharmacologic Therapy |
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1347 | (15) |
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118 Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death |
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1362 | (9) |
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119 Anticoagulation for Thromboembolic Prophylaxis |
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1371 | (12) |
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PART XVIII Devices for Arrhythmia Management |
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120 Implantable Pacemakers |
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1383 | (12) |
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121 Implantable Cardioverter-Defibrillators: Technical Aspects |
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1395 | (14) |
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122 Transvenous Implantable Cardioverter-Defibrillator: Clinical Aspects |
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1409 | (18) |
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123 Subcutaneous Implantable Cardioverter-Defibrillators |
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1427 | (11) |
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124 Wearable Defibrillators |
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1438 | (7) |
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125 Cardiac Resynchronization |
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1445 | (17) |
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126 Management of Implanted Device Infections |
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1462 | (9) |
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PART XIX Catheter and Surgical Mapping and Ablation |
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127 Electrogram Recording and Signal Processing |
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1471 | (15) |
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128 Electroanatomic Mapping for Arrhythmias |
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1486 | (17) |
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129 Mapping Scar-Related Arrhythmias |
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1503 | (13) |
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130 Radiofrequency Ablation |
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1516 | (15) |
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131 Cryoablation and Other Radiofrequency Alternatives |
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1531 | (12) |
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132 Transvascular Ethanol Ablation |
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1543 | (14) |
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133 Cardiac Radioablation |
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1557 | (9) |
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134 Epicardial Approach in Electrophysiology |
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1566 | (15) |
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135 Surgery for Atrial Fibrillation and Other Supraventricular Tachycardias |
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1581 | (17) |
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136 Surgery for Ventricular Arrhythmias |
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1598 | (11) |
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137 Neuromodulation for the Treatment of Arrhythmias |
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1609 | (12) |
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PART XX Drug Discovery for Cardiac Arrhythmias |
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138 Drug Discovery for Myocardial Diseases and Cardiac Arrhythmias Using Zebrafish |
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1621 | |
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