| Preface |
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xi | |
| Author Affiliation |
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xiii | |
| Acknowledgments |
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xvii | |
| About the Author |
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xxi | |
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PART I AN INTRODUCTION TO BIOSECURITY |
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1 | (48) |
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Chapter 1 Defining Biosecurity and Related Concepts |
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3 | (14) |
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3 | (1) |
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4 | (8) |
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Risk Management and Prioritization in Biosecurity |
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12 | (1) |
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Basic Components of Biosecurity |
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13 | (1) |
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14 | (3) |
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Chapter 2 Biosecurity as a Function of Biosafety Microbiological Laboratories |
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17 | (10) |
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17 | (1) |
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Evolving Steps towards Biosecurity |
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18 | (2) |
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Biosecurity is Embedded in Biosafety Programs |
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20 | (2) |
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Control Access to High-Consequence Pathogens and Toxins |
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22 | (1) |
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22 | (1) |
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Occupational Health Programs |
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23 | (1) |
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23 | (1) |
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24 | (3) |
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Chapter 3 A Perspective of Biosecurity: Past to Present |
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27 | (22) |
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27 | (1) |
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28 | (2) |
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30 | (4) |
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34 | (3) |
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37 | (4) |
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41 | (8) |
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PART II ELEMENTS OF BIOSECURITY |
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49 | (62) |
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Chapter 4 Physical Elements of Biosecurity |
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51 | (20) |
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51 | (1) |
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Protecting and Securing Biological Materials |
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51 | (7) |
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Breaking Down the Program: The Six Security Capabilities |
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58 | (5) |
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Architecture, Engineering and Work Practice Considerations |
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63 | (4) |
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Operations and Sustainment |
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67 | (3) |
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70 | (1) |
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Chapter 5 Operational Elements of Biosecurity |
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71 | (18) |
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71 | (1) |
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72 | (10) |
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Biosecurity Challenges Associated with Different Institutions |
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82 | (2) |
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New Regulatory Requirements |
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84 | (3) |
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87 | (2) |
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Chapter 6 Basic Principles of Threat Assessment |
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89 | (22) |
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89 | (1) |
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A Comprehensive Approach to Biosecurity |
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89 | (1) |
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Safety versus Security: Risk vesus Threat |
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90 | (12) |
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The Purposes and Requirements of Basic Suitability and Threat Assessment Programs |
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102 | (6) |
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108 | (3) |
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PART III BIOSECURITY IN VARIOUS SECTORS |
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111 | (74) |
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Chapter 7 Biosecurity in Research Laboratories |
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113 | (16) |
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113 | (1) |
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114 | (1) |
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115 | (7) |
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122 | (7) |
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Chapter 8 Biosecurity in the Food and Agricultural Industries |
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129 | (26) |
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129 | (1) |
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The U.S. Food and Agriculture Infrastructure |
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129 | (3) |
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132 | (13) |
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Food Defense: Protecting U.S. Food and Agriculture from Intentional Disruption |
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145 | (5) |
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150 | (5) |
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Chapter 9 Biosecurity in Mass Transportation Networks |
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155 | (12) |
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155 | (1) |
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Mass Transit Systems and Vulnerabilities |
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155 | (2) |
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Federal, State, and Local Biosecurity Activities and Planning |
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157 | (7) |
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164 | (3) |
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Chapter 10 Utilizing Biosecurity Principles to Combat Naturally Occurring Epidemics |
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167 | (18) |
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167 | (1) |
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Separating Deliberate Outbreaks from Naturally Occurring Epidemics |
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168 | (1) |
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The Need for Biosafety and Biosecurity in the Response to a Naturally Occurring Outbreak |
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169 | (3) |
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Assessing Biosafety and Biosecurity Risks in Public Health: The Science of Biosecurity |
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172 | (2) |
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Increasing Security Functions through the Application of Biosecurity to Public Health |
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174 | (1) |
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Challenges Associated with the International Coordination of Outbreak Response |
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175 | (3) |
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Biosecurity Impediments to International Health Programs |
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178 | (2) |
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180 | (5) |
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PART IV BIOSECURITY POLICY, BIOTERRORISM, AND THE FUTURE |
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185 | (81) |
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Chapter 11 Current Efforts to Fortify Biosecurity Policy in the U.S. |
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187 | (10) |
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187 | (1) |
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Emerging Policies Limiting Access to Pathogens and Enhancing Laboratory Security |
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188 | (3) |
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Policies that Focus on Dual-Use Research of Concern |
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191 | (1) |
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Evolving Oversight of Synthetic Biology |
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192 | (2) |
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194 | (3) |
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Chapter 12 The Link between Biosecurity and Bioterrorism |
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197 | (12) |
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197 | (1) |
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Bioterrorism Attack Cycle |
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197 | (5) |
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The Bioterrorism-Biosecurity Nexus |
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202 | (2) |
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The Biological Criminal Continuum |
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204 | (2) |
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206 | (3) |
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Chapter 13 The Importance of Engagement and Education for Effective Biosecurity |
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209 | (16) |
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209 | (1) |
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Overview of Engagement and Education |
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209 | (4) |
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Other Intervention Points and Actors |
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213 | (2) |
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Challenges Moving Forward |
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215 | (1) |
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Why Bother with Biosecurity-Related Education and Engagement? |
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216 | (2) |
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Moving Biosecurity Engagement and Education Forward |
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218 | (3) |
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221 | (4) |
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Chapter 14 Monitoring and Evaluating Laboratory Biosafety Programs |
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225 | (34) |
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225 | (2) |
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Need for a Laboratory Biosafety Program Framework |
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227 | (3) |
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Major Concepts and Definitions |
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230 | (9) |
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239 | (2) |
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Laboratory Biosafety Indicators |
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241 | (1) |
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Anticipated Benefits of the Indicator Database |
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242 | (1) |
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Analytic Processes to Refine Indicators |
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242 | (12) |
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254 | (1) |
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254 | (5) |
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Chapter 15 The Future of Biosecurity: A Global Context |
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259 | (7) |
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259 | (1) |
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259 | (3) |
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A One World/One Health Model for Biosecurity |
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262 | (4) |
| Future of Biosecurity |
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266 | (1) |
| Conclusion |
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267 | (4) |
| Appendix 1 U.S. Food Defense since 9/11: Public Sector Initiatives and Programs |
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271 | (18) |
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| Appendix 2 Timeline of Selected Events in Biosecurity Policy |
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289 | (10) |
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| Index |
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299 | |