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E-raamat: Evidence-Based Proactive Nutrition to Slow Cellular Aging

, (City University of New York-Hunter College)
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  • Ilmumisaeg: 18-Sep-2017
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781351700221
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Evidence-Based Proactive Nutrition to Slow Cellular AgingSuurem pilt
  • Formaat: PDF+DRM
  • Ilmumisaeg: 18-Sep-2017
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781351700221
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Recent research findings on the impact of nutrition on telomere length is unlocking the potential to combat premature aging at the cellular level. We have learned that while aging is a natural cellular process, premature aging is not and it can be positively impacted by an Evidence-Based Proactive Nutrition to Slow Cellular Aging diet plan.

This book examines key elements of the biology of cell aging and focuses on enhancing mitochondrial function and preventing abnormal cell turnover thus preserving telomere length. It details the cellular damage caused by free radicals and ROS, explains the salutary effects of antioxidants, and the bodys need for adequate nitrates and other nutrient substrates from which the body derives nitric oxide (NO) to support cardiovascular health. This book is the first to feature a simple do-it-yourself test of the effects of the diet on the availability of NO for - heart health.

The book guides the reader through the rationale for a modified Mediterranean style diet that supplies the body with an adequate daily intake of essential nutrients, simple high antioxidants, and other functional foods. It includes simple, easy to prepare appealing recipes promoting a seamless transition to a healthy, age-defying lifestyle.
Preface xvii
Acknowledgments xix
Authors xxi
Chapter 1 The Science of Longevity 1(20)
1.1 Introduction
1(1)
1.2 The Length of Telomeres Determines the Length of the Cell Lifespan
1(1)
1.3 Free Radicals Accelerate Aging
1(1)
1.4 Free Radicals Result in Shorter Telomeres
2(1)
1.5 A Proactive Nutrition Program Can Prevent Free Radical Cell Damage and Protect Telomeres
2(1)
1.6 Lifespan Cannot Be Lengthened But It Can Be Shortened
2(1)
1.7 Sources of Free Radicals
3(1)
1.8 Proactive Nutrition
3(1)
1.9 Documentation
3(1)
1.10 The Plan of the Book
4(1)
1.11 In the Beginning
5(1)
1.11.1 Mitochondria
5(1)
1.12 Aging Is Not a Disease
6(1)
1.13 Bio 101
6(1)
1.14 Can Aging Be Treated by Medicine?
7(1)
1.15 How Does the Body Change Naturally with Age?
8(9)
1.15.1 Blood Pressure
8(1)
1.15.2 Heart Function and Blood Vessels
9(1)
1.15.3 Blood Sugar and Insulin Function
10(1)
1.15.4 Decreased Insulin versus Resistance to Insulin
11(1)
1.15.5 Blood Lipids
11(1)
1.15.6 Body Fat Percentage and Body Mass Index
12(1)
1.15.7 Thyroid Function
13(1)
1.15.8 Kidney Function
14(1)
1.15.9 Steroid Hormones
14(1)
1.15.9.1 The Immune System
14(1)
1.15.9.2 Blood Sugar Metabolism/Weight Management
15(1)
1.15.9.3 Heart Disease
15(1)
1.15.9.4 Estrogen/Testosterone Levels
15(1)
1.15.10 Bones, Muscles, and Joints
15(1)
1.15.11 Antioxidant Defenses
16(1)
References
17(4)
Chapter 2 Free Radicals Damage Cells 21(14)
2.1 Introduction
21(1)
2.2 Why Do We Age?
21(1)
2.3 What Is the Biological Clock?
22(1)
2.4 What Jeopardizes Longevity?
22(2)
2.4.1 What Are Free Radicals?
23(1)
2.4.2 Free Radical Sources from Cell Metabolism
23(1)
2.5 What Are Reactive Oxygen Species?
24(1)
2.5.1 Antioxidants
24(1)
2.6 Accelerated Cell Division, Repair, or Self-Destruction
25(1)
2.7 Exogenous Free Radicals
25(5)
2.7.1 Example 1: Ultraviolet Radiation in Sunlight Shortens Telomeres
25(1)
2.7.2 Sirtuins and Photodamage
26(1)
2.7.3 Example 2: "Smoke! Smoke! Smoke! (That Cigarette)"
26(1)
2.7.4 Smoking Cigarettes Shortens Telomeres
27(1)
2.7.5 Example 3: Free Radicals from Smog and Air Pollution
28(1)
2.7.6 Health Consequences of Smog
28(1)
2.7.7 Air Pollution Damages Telomeres
28(1)
2.7.8 Example 4: Inflammation Causes Oxidative Stress
29(1)
2.7.9 Example 5: Immune Response and ROS
29(1)
2.8 Endogenous Free Radicals
30(1)
2.9 Theory: Free Radicals Cause Aging
30(1)
2.10 Beneficial Effects of Free Radicals in Immune Defense
31(1)
References
32(3)
Chapter 3 Antioxidants Neutralize Free Radicals 35(36)
3.1 Introduction
35(1)
3.2 What Are Antioxidants?
35(1)
3.3 Levels of Antioxidant Action
36(1)
3.4 The Antioxidants the Body Makes
36(3)
3.4.1 Superoxide Dismutase(s) (SODs)
37(1)
3.4.2 Buyer Beware
37(1)
3.4.3 Catalase (CAT)
37(1)
3.4.4 Glutathione (GSH) System: Glutathione Peroxidase(s) (GPx)
38(1)
3.4.5 Ubiquinone, also Known As Coenzyme Q10 (CoQ10)
38(1)
3.4.6 Alpha-Lipoic Acid (ALA)
39(1)
3.5 Telomeres Shorten When Endogenous Antioxidants Fail
39(1)
3.6 Age-Related Decline in Endogenous Antioxidants
40(2)
3.7 Exogenous Antioxidants
42(1)
3.8 Quantitative Measures of Antioxidant Capacity
42(5)
3.8.1 Thiobarbituric Acid Reactive Substances (TBARS)
42(1)
3.8.2 Oxygen Radical Absorbance Capacity (ORAL)
43(3)
3.8.3 Trolox Equivalent Antioxidant Capacity (TEAC)
46(1)
3.9 Maintaining a Healthy Balance
47(1)
3.10 Plant and Other Food-Based Antioxidants
48(2)
3.10.1 Polyphenols
48(1)
3.10.2 Anti-Aging Effect of Polyphenols
49(1)
3.11 Carotenoids
50(2)
3.11.1 Examples of Carotenoid Sources
50(1)
3.11.2 Additional Vitamin Antioxidants: Vitamins A, C, E
50(3)
3.11.2.1 Vitamin A
51(1)
3.11.2.2 Vitamin C
51(1)
3.11.2.3 Vitamin E
51(1)
3.12 When It Comes to Vitamins, More Is Not Always Better
52(1)
3.13 Resveratrol
52(1)
3.14 Quercetin
53(1)
3.15 Black/Green Tea, Coffee, and Cocoa
53(1)
3.15.1 Black Tea versus Green Tea versus Red Wine versus Cocoa
53(1)
3.16 Antiradical versus Antioxidant
54(1)
3.17 Red Wine
54(4)
3.17.1 Resveratrol in Red Wines
55(1)
3.17.2 Caution about Wine as A Nutritional Source
55(2)
3.17.3 Alcohol Depletes Vitamins
57(1)
3.17.3.1 Thiamin, Niacin, and Pyridoxine
57(1)
3.17.3.2 Riboflavin and B12
57(1)
3.17.3.3 Ascorbic Acid and Fat-Soluble Vitamins
58(1)
3.17.4 Astaxanthin
58(1)
3.18 Plants As a Source of Antioxidants
58(1)
3.19 Antioxidants Protect Telomeres
59(1)
3.20 Regular Vitamin Consumption Protects Telomeres
59(1)
3.20.1 Dietary Intake of Antioxidants Reduces the Rate of Telomeres Shortening
59(1)
3.20.2 Dietary Antioxidant Intake Affects Breast Cancer Risk and Telomere Length in Women
60(1)
3.21 One Can't Start Early Enough
60(1)
3.22 The Impact of Differences in Regional Dietary Antioxidant Intake on Aging
60(1)
3.23 Why It Is Wise to Consider the Mediterranean Diet
61(1)
3.24 Tea Is the Beverage of Choice with the Mediterranean Diet
61(1)
3.25 Aging Is an Equal Opportunity Issue
62(1)
3.26 Consuming Vegetables Protects Telomeres
62(1)
3.27 If "Some Antioxidants" Are Good, Are "More" Better
62(2)
3.28 Food Sources versus Supplements
64(1)
References
64(7)
Chapter 4 Preventing Premature Cell Cycling 71(18)
4.1 Introduction
71(1)
4.2 Body Weight May Be an Unreliable Clue to Cell Aging
72(1)
4.3 Cell Division: Mitosis
72(1)
4.4 Cell Suicide: Apoptosis
73(1)
4.5 The Cell-Owner's Manual
73(6)
4.5.1 The Membrane
74(2)
4.5.1.1 Reactive Oxygen Species (ROS): Cell Killers
75(1)
4.5.2 The Nucleus
76(1)
4.5.2.1 Chromosomes
76(1)
4.5.3 Endoplasmic Reticulum
77(1)
4.5.4 The Mitochondria
77(3)
4.5.4.1 The Mitochondrial Theory of Aging
78(1)
4.6 Free Radicals: Inside and Outside the Cell
79(1)
4.7 What Triggers Mitosis?
79(1)
4.8 Can Telomere Length Be Directly Controlled?
80(1)
4.8.1 Telomerase
80(1)
4.8.1.1 Meditation and Telomeres
80(1)
4.9 The Proactive Nutrition Program
81(1)
4.10 The Sirtuin Family
81(3)
4.10.1 Sirtfoods Protect the Cell Membrane, Organelles, and Telomeres
82(1)
4.10.2 Sirtuin and Cancer: The Possible Dark Side of SIRT1
83(1)
4.10.3 Sirtuin and Cancer: The Possible Bright Side of SIRT1
84(1)
4.11 20:20 Hindsight
84(1)
References
85(4)
Chapter 5 Nitric Oxide Is Said to Be the "Miracle Molecule" That "Reverses Aging" 89(34)
5.1 Introduction
89(1)
5.2 How the Body Forms Nitric Oxide
89(1)
5.3 The Laboratory Oversight That Led to the Nobel Prize
90(2)
5.3.1 A Simple Error
91(1)
5.4 Nitric Oxide Derived from L-Arginine
92(1)
5.5 Nitric Oxide Derived from Nitrates
93(3)
5.5.1 The "Nitrites Cause Cancer" Controversy
95(1)
5.6 How Does NO Control Blood Flow in Blood Vessels?
96(1)
5.7 The Endothelial Flow-Mediated Dilation Test Measures The Effects of NO on Blood Vessels
97(1)
5.8 Oral L-Arginine versus Oral L-Citrulline
98(1)
5.9 Blood Pressure
98(4)
5.9.1 Blood Pressure Normally Rises Progressively with Age
99(1)
5.9.2 Dietary L-Arginine and the Arginine Paradox
100(1)
5.9.3 Nitric Oxide from Dietary L-Arginine and Nitrate Lowers Blood Pressure
101(1)
5.9.4 "Beet" the Clock
101(4)
5.9.4.1 The Case for Supplements versus Beets
102(1)
5.10 Ferric Reducing Antioxidant Power (FRAP) Assay
102(3)
5.11 Atherosclerosis
105(2)
5.11.1 Preventing, Even Reducing, Atherosclerosis with Dietary L-Arginine and Nitrate
105(2)
5.11.2 Dietary Nitrate Improves Blood Circulation in Atherosclerosis
107(1)
5.12 Heart Disease
107(2)
5.12.1 Heart Disease Patients Improve with Dietary Nitrate or L-Arginine
108(1)
5.12.2 Congestive Heart Failure Reduced by Dietary L-Arginine or Nitrate
109(1)
5.12.3 An Important Consideration
109(1)
5.13 Peripheral Artery Disease
109(2)
5.13.1 The Ankle-Brachial Index
110(1)
5.14 Metabolic Syndrome and Type 2 Diabetes
111(1)
5.14.1 The Role of Mitochondria in Metabolic Syndrome
111(1)
5.14.2 Dietary L-Arginine and Nitrate in the Treatment of Metabolic Syndrome and Type 2 Diabetes
111(1)
5.14.3 L-Arginine and Glucose Tolerance
112(1)
5.15 Dietary L-Arginine and Nitrate in Kidney Dysfunction
112(1)
5.16 NO Protects Telomeres
112(1)
5.17 Nitric Oxide Concentration Is Usually Measured Indirectly (NOx), but Can It Be Measured Directly?
113(1)
5.18 Measuring NO in Clinical Outcome
114(2)
5.18.1 Measuring NO in Exhaled Air
115(1)
5.18.2 Measuring NO in Serum or Plasma
115(1)
5.19 NOx Self-Test
116(1)
References
117(6)
Chapter 6 Three Common Diets Compared for Their Effects on Cell Aging 123(30)
6.1 Introduction
123(1)
6.2 Oxidative Metabolism
123(2)
6.3 How and Why Nutrition Guidelines Change Over Time
125(1)
6.4 Early Food Guidance: 1900s-1940s
126(1)
6.5 Dietary Guidance: 1940s to 1970s
126(1)
6.6 The Early 1970s to the 1990s
127(1)
6.7 1984 Food Wheel: A Pattern for Daily Food Choices
128(2)
6.7.1 The 1992 Food Guide Pyramid
128(1)
6.7.2 The Nutrition Facts Label
129(1)
6.8 Some Basic Relevant Health Hazard Statistics
130(1)
6.9 From 1995 to the Present
130(2)
6.10 The Carnival Mirror
132(1)
6.11 A Note on Omission of Antioxidant Capacity in Food Guidelines
132(1)
6.12 The Pharmacokinetics of Antioxidants
133(1)
6.13 The Prudent Diet
134(1)
6.14 The Western Diet, also Known As the SAD
134(6)
6.14.1 The Western Diet Compromises Health
135(1)
6.14.2 The Western Diet and Obesity
136(1)
6.14.3 The Western Diet and Metabolic Syndrome
136(1)
6.14.4 Metabolic Syndrome Shortens Telomeres
137(1)
6.14.5 The Western Diet and Hypertension
137(1)
6.14.6 The Western Diet and Cardiovascular and Heart Disease
138(1)
6.14.6.1 Cardiovascular and Heart Disease Shorten Telomeres
139(1)
6.14.7 The Western Diet and Type 2 Diabetes
139(1)
6.14.7.1 Type 2 Diabetes Shortens Telomeres
139(1)
6.15 The Proactive Nutrition Program
140(2)
6.15.1 The Mediterranean Pattern Diet
140(4)
6.15.1.1 The Mediterranean Pattern Diet Protects Telomeres
141(1)
6.15.1.2 The Mediterranean Diet Activates Sirtuin 1
141(1)
6.15.1.3 The Mediterranean Diet and Obesity
141(1)
6.15.1.4 The Mediterranean Diet and Metabolic Syndrome
142(1)
6.16 Promoting Sirtuins
142(1)
6.17 Hypertension and Cardiovascular and Heart Function: Comparing the Mediterranean Diet to Another Low-Fat Diet
143(1)
6.18 The Mediterranean Diet and Elevated Serum Cholesterol
143(1)
6.19 The Mediterranean Diet and Hypertension
144(1)
6.20 The Mediterranean Diet and Endothelium Function
144(1)
6.20.1 Averting Premature Aging of the Endothelium
144(1)
6.21 Sirtuins and Blood Vessel and Heart Health
145(1)
6.21.1 Sirtuin 1 and Coronary Heart Disease
145(1)
6.22 The Mediterranean Diet and Type 2 Diabetes
145(1)
6.23 Activating Sirtuins Improves Type 2 Diabetes
146(1)
6.24 A Note on Caloric Restriction
146(1)
6.25 The Secret Revealed
146(1)
6.26 The Case for the Proactive Nutrition Program
147(1)
References
147(6)
Chapter 7 Proactive Nutrition: Enhancing the Mediterranean Diet 153(56)
7.1 "The Canary in the Coal Mine"
153(1)
7.2 The Link to Averting Premature Aging
154(1)
7.3 Three Food Factors in the Mediterranean Diet Enhance Health, Vitality, and Longevity
154(1)
7.4 The Enhanced Mediterranean Diet Is the Proactive Nutrition Program
155(1)
7.5 A Note on "Sirtfoods"
156(1)
7.6 The Proactive Nutrition Program Is Not Simply a Diet
156(3)
7.6.1 The Smart Shopping Cart
156(2)
7.6.2 A Basic Shopping List for the Diet
158(1)
7.7 The ABCs of Eating
159(1)
7.8 "The Eyes Are Bigger than the Stomach"
160(2)
7.8.1 The "Completion Compulsion"
160(1)
7.8.2 Counting Calories
161(1)
7.8.3 Putting the "e" Back into Eating
161(1)
7.9 The Secret of the Mediterranean Diet: Greens and Beans, and NO Donors
162(2)
7.10 A Salivary Marker of NO Availability: The HumanN™ N-O Indicator Strips
164(2)
7.11 Implementing the Basic Mediterranean Food Plan and Sample Recipes
166(1)
7.12 Sample Mediterranean Diet Meal Plan
167(10)
7.12.1 First, a Note on Olive Oil
167(2)
7.12.2 A Note on Palm Oil
169(2)
7.12.3 And a Note on Coconut Oil
171(3)
7.12.4 Extra-Virgin Olive Oil and the Xenohormesis Hypothesis: When Plants "Talk" to the Animals, What Do They Tell Them?
174(3)
7.13 Seven-Day Food Plan
177(3)
7.13.1 Serving Sizes, Kitchen Measures, and Metric Conversion
177(1)
7.13.2 Monday
178(1)
7.13.3 Tuesday
179(1)
7.13.4 Wednesday
179(1)
7.13.5 Thursday
179(1)
7.13.6 Friday
179(1)
7.13.7 Saturday
179(1)
7.13.8 Sunday
180(1)
7.14 Selected Recipes
180(23)
7.14.1 Breakfast Dishes
180(3)
7.14.1.1 Vegetable Omelet
180(1)
7.14.1.2 Zucchini and Goat Cheese Frittata
181(1)
7.14.1.3 Lemon Scones
181(1)
7.14.1.4 Breakfast Mango Smoothies
182(1)
7.14.1.5 Breakfast Berry Smoothie
182(1)
7.14.2 Soups, Salads, and Side Dishes
183(7)
7.14.2.1 Bean and Macaroni Soup
183(1)
7.14.2.2 Minestrone Soup
184(1)
7.14.2.3 Gazpacho
184(1)
7.14.2.4 Rockport Fish Chowder
185(1)
7.14.2.5 Cannery Row Soup
186(1)
7.14.2.6 Chicken Salad
186(1)
7.14.2.7 Spinach Salad
187(1)
7.14.2.8 Sunshine Salad
187(1)
7.14.2.9 Fresh Cabbage and Tomato Salad
188(1)
7.14.2.10 Waldorf Salad
188(1)
7.14.2.11 Stuffed Artichokes
189(1)
7.14.3 Entrees
190(8)
7.14.3.1 Chicken Orientale
190(1)
7.14.3.2 Chicken Ratatouille
190(1)
7.14.3.3 Scallop Kabobs
191(1)
7.14.3.4 Mediterranean Baked Fish
192(1)
7.14.3.5 Spinach-Stuffed Sole
192(1)
7.14.3.6 Black Beans with Rice
193(1)
7.14.3.7 New Orleans Red Beans
194(1)
7.14.3.8 Summer Vegetable Spaghetti
194(1)
7.14.3.9 Zucchini Lasagna
195(1)
7.14.3.10 Italian Vegetable Bake
196(1)
7.14.3.11 Smothered Greens
196(1)
7.14.3.12 Fusilli Diablo
197(1)
7.14.3.13 Oriental Rice
198(1)
7.14.4 Sauces and Dressing
198(1)
7.14.4.1 Fresh Salsa
198(1)
7.14.4.2 Vinaigrette Salad Dressing
199(1)
7.14.4.3 Yogurt Salad Dressing
199(1)
7.14.5 Desserts
199(4)
7.14.5.1 Rainbow Fruit Salad
199(1)
7.14.5.2 Banana Mousse
200(1)
7.14.5.3 Rice Pudding
200(1)
7.14.5.4 Poached Pears with Raspberries
201(1)
7.14.5.5 Baked Apples
202(1)
7.15 The Proactive Nutrition Program Sample Sirtfood and Smoothie Recipes
203(3)
7.15.1 Sample Sirtfoods
204(1)
7.15.2 Sample Recipes
204(1)
7.15.2.1 Turmeric Cauliflower
204(1)
7.15.2.2 French Onion Soup
205(1)
7.15.3 Sample Smoothies
205(8)
7.15.3.1 Cacao Passion Sirt-Smoothie
205(1)
7.15.3.2 Kale-Apple Super Sirt-Smoothie
205(1)
7.15.3.3 Parsley Go Bananas Sirt-Smoothie
206(1)
References
206(3)
Chapter 8 Selected Functional Foods That Combat Inflammation 209(44)
8.1 Introduction
209(1)
8.2 Functional Foods
210(1)
8.3 The Two-Pronged Approach to Antioxidation
211(1)
8.4 Inflammation Causes Oxidative Stress
211(2)
8.5 C-Reactive Protein: A Standard Marker of Inflammation
213(2)
8.5.1 CRP and COPD
213(1)
8.5.2 CRP and Periodontal Disease
214(1)
8.5.3 CRP and Helicobacter pylori Infection
214(1)
8.6 "Inflamm-Aging"
215(1)
8.6.1 Chronic Inflammation Shortens Telomeres
215(1)
8.7 Functional Foods That Fight Inflammation
216(8)
8.7.1 Ginger (Zingiber officinale Roscoe)
216(3)
8.7.1.1 Ginger and Type 2 Diabetes
217(1)
8.7.1.2 Ginger and Periodontal Disease
218(1)
8.7.1.3 Periodontal Disease Is Associated with Shorter Telomeres
218(1)
8.7.1.4 How Safe Is Consumption of Ginger?
218(1)
8.7.2 Mostly Green Tea
219(5)
8.7.2.1 Tea Lowers Inflammation
220(1)
8.7.2.2 Tea Normalizes Insulin Sensitivity and Sugar Metabolism
220(1)
8.7.2.3 Tea Reduces Inflammation and Protects Blood Vessels by Promoting Endothelium NO Formation
221(1)
8.7.2.4 A Green Tea Constituent Protects Telomeres
221(1)
8.7.2.5 It Is Best to Leave Out the Milk
222(1)
8.7.2.6 Green Tea versus Black Tea and Brewing "Loose" Tea versus Tea Bags: The Case for Lower Oxalate Levels
222(1)
8.7.2.7 Is It Safe to Drink a Lot of Tea?
223(1)
8.8 Hot Chili Peppers
224(2)
8.8.1 Substance P Is Also Implicated in Depression
224(1)
8.8.2 Capsicum baccatum Is Anti-Inflammatory
225(1)
8.9 Cinnamon
226(3)
8.9.1 Cinnamon Is Antioxidant
226(1)
8.9.2 Cinnamon Is Anti-Inflammatory
227(1)
8.9.3 Cinnamon and Type 2 Diabetes
227(2)
8.9.4 Safety of Cinnamon
229(1)
8.10 Edible Seaweed, a Sea Vegetable
229(4)
8.10.1 The Barnes Test
230(1)
8.10.2 Kelp Is on the Way
231(1)
8.10.3 Iodine Content of Different Varieties of Seaweed
231(1)
8.10.4 Health Risks of Excessive Iodine Intake
232(1)
8.10.5 Interaction with Medications
232(1)
8.10.5.1 Anti-Thyroid Medications
232(1)
8.10.5.2 Angiotensin-Converting Enzyme (ACE) Inhibitors
233(1)
8.10.5.3 Potassium-Sparing Diuretics
233(1)
8.11 Mastic: Pistacia lentiscus var. chia
233(5)
8.11.1 Mastic Is Anti-Inflammatory
234(1)
8.11.2 A Mediterranean Spice That Targets H. pylori
234(2)
8.11.3 Mastic Lowers Oxidative Stress
236(1)
8.11.4 Mastic Targets the Bacteria That Cause Periodontitis
236(1)
8.11.5 Mastic Protects the Heart
237(1)
8.11.6 Anemia: H. pylori Is an Iron Glutton
237(1)
8.11.6.1 Serum Ferritin
237(1)
8.12 Elderberry (Sambucus nigra canadensis)
238(2)
8.12.1 Elderberry Is Antioxidant and Reduces Inflammation and Oxidative Stress
238(1)
8.12.2 Acute Inflammation versus Chronic Inflammation
239(1)
8.13 Turmeric
240(1)
8.13.1 Curcumin Is Antioxidant and Anti-Inflammatory
240(1)
8.13.2 Is It Safe to Consume Curcumin
241(1)
8.14 Supplements
241(2)
8.14.1 Zinc Is Antioxidant, Anti-Inflammatory, and Protects Telomeres
241(1)
8.14.2 Magnesium Is Anti-Inflammatory and Protects Telomeres
242(1)
8.14.3 Niacin Reduces Oxidative Stress
242(1)
8.15 Taurine
243(1)
8.15.1 Taurine Helps Maintain Muscles in Aging
243(1)
8.15.2 Taurine Has Beneficial Effects in Type 1 and Type 2 Diabetes
244(1)
8.16 Final Note
244(1)
References
244(9)
Index 253
Dr. Robert Fried was born in Linz, Austria, immigrated to the United States, and served in the Signal Corps, US Army, supporting radio communications for the Korean Military Advisory Group (KMAG), Seoul, Korea. Following honorable discharge, he entered The City College of New York (CCNY) and then the graduate program at Rutgers University, New Brunswick, New Jersey, earning his PhD in physiological psychology. Dr. Fried was appointed to the faculty of Hunter College, City University of New York (CUNY), as well as the Doctoral Faculty in Behavioral Neuroscience at the City University of New York (CUNY). He is licensed in clinical psychology in New York State and served for 4 years as Director of the Rehabilitation Research Institute (RRI), International Center for the Disabled (ICD), New York, where he conducted and later published his research on the control of blood gases and blood pH in idiopathic seizure disorders. He was research scientist, Aviation Medical Acceleration Laboratory (Project Mercury); research associate, Eastern Pennsylvania Psychiatric Institute (EPPI), Temple University Medical School, and adjunct assistant professor, The University of Pennsylvania, both in Philadelphia; research psychologist, Atascadero State Hospital for the Criminally Insane Sex Offender, Pasa Robles, California, and visiting professor, California Polytechnic State University, San Luis Obispo; research associate, Department of Community Health, Albert Einstein College of Medicine; and research associate, Payne Whitney Clinic, Cornell University Medical School. He retired from CUNY in 2010 as Professor Emeritus. Dr. Fried has lectured extensively in the United States and abroad and has conducted numerous workshops on respiratory and cardiovascular psychophysiology and blood gas self-regulation in neurological disorders, cardiovascular function, and stress syndrome. He holds a number of US patents in biomedical instrumentation including one of the earliest ECG-heart rhythm analyzer/computers. Dr. Fried has authored more than 45 scientific publications in peer-reviewed journals as well as scientific textbooks, including Erectile Dysfunction As a Cardiovascular Impairment (Elsevier/Academic Press, 2014) and The Psychology and Physiology of Breathing in Behavioral Medicine, Clinical Psychology & Psychiatry (Springer, 1993). Dr. Fried has also authored several consumer health self-help books including The Arginine Solution (Fried and Merrell, Time/Warner Books, 1999) and Great Food/Great Sex: The Three Food Factors for Sexual Fitness (Fried and Edlen- Nezin, Balantine Books, 2006). He has been featured in popular health magazine such as Mens Health and Prevention and interviewed on national and international TV including Fox News and CNN. Dr. Fried is Emeritus Member of the American Physiological Society (APS) (Cardiovascular and Respiration division); Fellow, NY Academy of Sciences (NAS); and Diplomate in Behavioral Medicine, International Academy of Behavioral Medicine, Counseling and Psychotherapy (IABMCP); and he is listed in the Centennial Edition of Marquis Whos Who. He lives in New York City with his wife Robin, a violinist with the Orchestra of St. Lukes, the Westchester Symphony Orchestra, and the American Ballet Theater (ABT) Orchestra.



Dr. Lynn Nezin is a senior strategic planner for FCB Health in New York City. She completed her doctorate in clinical health psychology in a joint program with the Ferkauf School of Psychology and Albert Einstein College of Medicine, Yeshiva University, and did her predoctoral internship at the St. Lukes Roosevelt Obesity Research Center in New York City. At the age of 12, Dr. Nezins family moved to the US Virgin Islands, where she learned to ride horses, sing with a Spanish Christmas carol chorus, and play the flute in the high school marching band. The band went on to perform at the Worlds Fair and also marched in the Veterans Day parade in Washington, DC. Dr. Nezin was among the first personal trainers to be certified by the American College of Sports Medicine. She initiated the employee fitness program at Rockefeller University and was head trainer at the Sports Training Institute, the first one-on-one fitness gym in New York City. A former competitive racewalker, Lynn completed four New York City Marathons. Dr. Nezin has collaborated on a number of health and nutrition-related federallyfunded research programs with the division of epidemiology and social medicine at Albert Einstein and also at the American Health Foundation, under the direction of the late Dr. Ernst Wynder. She has coauthored a number of peer-reviewed journal articles and textbook chapters on behavioral health and nutrition and coauthored Great Food, Great Sex: The Three Food Factors for Sexual Fitness (Ballantine Books, 2006) with Dr. Robert Fried. Dr. Nezin was one of the founding organizers of the Health 2.0 NYC Technology Meetup group, which now numbers more than 1000 members devoted to innovation in public and personal health. She is a member of the American Diabetes Association and has been featured in Cambridge Whos Who.
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