Preface |
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xi | |
Acknowledgements |
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xv | |
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1 | (90) |
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1 Introduction to Nanotechnology |
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3 | (16) |
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1.1 Nanotechnology: From Large to Small |
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3 | (5) |
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1.1.1 Feynman: Plenty of Room at the Bottom |
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3 | (3) |
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1.1.2 Nanotechnology Today |
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6 | (1) |
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1.1.3 The Bottom-Up Approach |
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7 | (1) |
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1.2 Nanocarbons: Now and Then |
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8 | (11) |
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9 | (1) |
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9 | (2) |
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11 | (2) |
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13 | (2) |
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15 | (4) |
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19 | (18) |
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2.1 Ah, Diamonds, Eternal Beautiful |
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19 | (3) |
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2.2 Diamonds: From Structure to Classification |
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22 | (4) |
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22 | (2) |
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24 | (2) |
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26 | (4) |
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27 | (2) |
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29 | (1) |
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30 | (1) |
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2.4 Nanodiamonds: A Scientist's Best Friend |
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30 | (7) |
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33 | (4) |
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3 Color Centers in Diamond |
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37 | (18) |
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37 | (3) |
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40 | (1) |
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3.3 Vacancy-Related Color Centers |
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41 | (6) |
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41 | (3) |
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44 | (2) |
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46 | (1) |
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46 | (1) |
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47 | (8) |
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50 | (5) |
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4 Surface Chemistry of Nanodiamonds |
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55 | (18) |
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56 | (5) |
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61 | (5) |
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4.2.1 Noncovalent Conjugation |
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61 | (3) |
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4.2.2 Covalent Conjugation |
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64 | (2) |
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66 | (7) |
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66 | (1) |
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67 | (2) |
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69 | (4) |
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5 Biocompatibility of Nanodiamonds |
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73 | (18) |
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5.1 Biocompatibility Testing |
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73 | (4) |
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74 | (2) |
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76 | (1) |
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76 | (1) |
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77 | (5) |
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77 | (3) |
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80 | (2) |
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82 | (1) |
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83 | (8) |
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86 | (5) |
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91 | (180) |
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6 Producing Fluorescent Nanodiamonds |
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93 | (20) |
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93 | (8) |
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6.1.1 Theoretical Simulations |
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93 | (3) |
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6.1.2 Electron/Ion Irradiation |
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96 | (3) |
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99 | (2) |
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101 | (12) |
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6.2.1 Fluorescence Intensity |
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101 | (3) |
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6.2.2 Electron Spin Resonance |
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104 | (1) |
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6.2.3 Fluorescence Lifetime |
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105 | (2) |
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6.2.4 Magnetically Modulated Fluorescence |
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107 | (3) |
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110 | (3) |
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7 Single Particle Detection and Tracking |
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113 | (622) |
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7.1 Single Particle Detection |
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113 | (7) |
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113 | (4) |
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7.1.2 Spectroscopic Properties |
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117 | (1) |
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7.1.3 Color Center Numbers |
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118 | (2) |
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7.2 Single Particle Tracking |
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120 | (615) |
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7.2.1 Tracking in Solution |
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120 | (2) |
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122 | (5) |
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7.2.3 Tracking in Organisms |
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127 | (3) |
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130 | (605) |
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8 Cell Labeling and Fluorescence Imaging |
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735 | (20) |
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135 | (7) |
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8.1.1 Nonspecific Labeling |
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136 | (3) |
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139 | (3) |
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142 | (613) |
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8.2.1 Epifluorescence and Confocal Fluorescence |
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142 | (2) |
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8.2.2 Total Internal Reflection Fluorescence |
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144 | (2) |
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8.2.3 Two-Photon Excitation Fluorescence |
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146 | (1) |
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8.2.4 Time-Gated Fluorescence |
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147 | (3) |
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150 | (605) |
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9 Cell Tracking and Deep Tissue Imaging |
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155 | (1) |
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155 | (1) |
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155 | (3) |
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158 | (601) |
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159 | (2) |
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161 | (4) |
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161 | (2) |
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163 | (2) |
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165 | (5) |
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9.3.1 Wide-Field Fluorescence Imaging |
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165 | (4) |
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9.3.2 Optically Detected Magnetic Resonance Imaging |
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169 | (1) |
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9.3.3 Time-Gated Fluorescence Imaging |
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170 | (1) |
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93 A Magnetically Modulated Fluorescence Imaging |
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170 | (605) |
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171 | (604) |
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775 | (20) |
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176 | (1) |
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10.2 Superresolution Fluorescence Imaging |
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177 | (7) |
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10.2.1 Stimulated Emission Depletion Microscopy |
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177 | (4) |
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10.2.2 Saturated Excitation Fluorescence Microscopy |
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181 | (1) |
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10.2.3 Deterministic Emitter Switch Microscopy |
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182 | (1) |
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10.2.4 Tip-Enhanced Fluorescence Microscopy |
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183 | (1) |
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10.3 Cathodoluminescence Imaging |
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184 | (4) |
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10.4 Correlative Light-Electron Microscopy |
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188 | (3) |
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191 | (4) |
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11 Nanoscale Quantum Sensing |
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195 | (1) |
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11.1 The Spin Hamiltonian |
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196 | (1) |
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197 | (1) |
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11.2.1 Ultrahigh Precision Temperature Measurement |
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197 | (3) |
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11.2.2 Time-Resolved Nanothermometry |
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200 | (3) |
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11.2.3 All-Optical Luminescence Nanothermometry |
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203 | (2) |
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11.2.4 Scanning Thermal Imaging |
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205 | (2) |
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207 | (8) |
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11.3.1 Continuous-Wave Detection |
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207 | (3) |
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210 | (1) |
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211 | (4) |
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12 Hybrid Fluorescent Nanodiamonds |
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215 | (20) |
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12.1 Silica/Diamond Nanohybrids |
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215 | (2) |
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12.2 Gold/Diamond Nanohybrids |
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217 | (9) |
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12.2.1 Photoluminescence Enhancement |
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217 | (1) |
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12.2.2 Dual-Modality Imaging |
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218 | (2) |
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12.2.3 Hyperlocalized Hyperthermia |
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220 | (4) |
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12.2.4 NV-Based Nanothermometry |
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224 | (2) |
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12.3 Silver/Diamond Nanohybrids |
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226 | (2) |
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12.4 Iron Oxide/Diamond Nanohybrids |
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228 | (7) |
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12.4.1 Single-Domain Magnetization |
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228 | (1) |
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12.4.2 Magnetic Resonance Imaging |
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229 | (3) |
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232 | (3) |
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13 Nanodiamond-Enabled Medicine |
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235 | (18) |
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13.1 NDs as Therapeutic Carriers |
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236 | (1) |
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237 | (7) |
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237 | (4) |
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241 | (3) |
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244 | (3) |
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244 | (1) |
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245 | (2) |
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247 | (6) |
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249 | (4) |
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253 | (18) |
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14.1 Unidentified Infrared Emission |
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253 | (5) |
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14.2 Extended Red Emission |
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258 | (6) |
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14.3 Cosmic Events at Home on Earth |
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264 | (7) |
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267 | (4) |
Further Reading |
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271 | (2) |
Index |
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273 | |