| Preface |
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xi | |
| Acknowledgment |
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xiii | |
| About the Editor |
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xv | |
| Contributors |
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xvii | |
| Section I Introduction: Structure and Function of Mitochondria |
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Chapter 1 Mitochondrial Structure and Function |
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3 | (6) |
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Marcos Roberto de Oliveira |
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Chapter 2 Structure, Function and Evolutionary Aspects of Mitochondria |
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9 | (14) |
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Chapter 3 Mitochondrial Genome Damage, Dysfunction and Repair |
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23 | (16) |
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| Section II Mitochondrial Dysfunction and Diseases |
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Chapter 4 Instability of Human Mitochondrial DNA, Nuclear Genes and Diseases |
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39 | (16) |
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Chapter 5 Kearns-Sayre Syndrome |
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55 | (6) |
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Chapter 6 Mitochondrial Dysfunction and Barth Syndrome |
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61 | (18) |
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Chapter 7 Mitochondrial Dysfunction in the Pathophysiology of Alzheimer's Disease |
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79 | (8) |
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Chapter 8 Mitochondrial Dysfunction in Multiple Sclerosis |
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87 | (6) |
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Chapter 9 Mitochondrial Dysfunction in Chronic Kidney Disease |
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93 | (10) |
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Chapter 10 Mitochondrial Dysfunction in Breast Cancer: A Potential Target from the Bench to Clinical Therapeutics |
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103 | (12) |
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Leticia Madureira Pacholak |
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Chapter 11 Mitochondrial Dysfunction and DNA Methylation in Atherosclerosis |
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115 | (12) |
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Chapter 12 Mitochondrial Dysfunction and Heart Diseases |
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127 | (16) |
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Chapter 13 The Role of Mitochondrial Dysfunction in Mitophagy and Apoptosis and Its Relevance to Cancer |
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143 | (8) |
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Chapter 14 Mitochondrial Dysfunction Linking Obesity and Asthma |
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151 | (12) |
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Chapter 15 Mitochondrial Dysfunction and Hearing Loss |
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163 | (8) |
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Maria de la Luz Arenas Sordo |
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Chapter 16 Superoxide Dismutase, Mitochondrial Dysfunction, and Neurodegenerative Diseases |
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171 | (20) |
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Chapter 17 Role of Post-Translational Modifications of Mitochondrial Complex I in Mitochondrial Dysfunction and Human Brain Pathologies |
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191 | (14) |
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Muchukunte Mukunda Srinivas Bharath |
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Chapter 18 Heme Oxygenase-1 in Kidney Health and Disease: Perspective of Mitochondrial Homeostasis |
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205 | (12) |
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Chapter 19 Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury |
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217 | (14) |
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Chapter 20 Mitochondrial Dysfunction in Diabetes |
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231 | (12) |
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Chapter 21 Clinical Manifestation of Mitochondrial Disorders in Childhood |
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243 | (22) |
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Chapter 22 Mitochondrial Dysfunction and Epilepsies |
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265 | (12) |
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Chapter 23 Mitochondrial Dysfunction and Allergic Disease |
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277 | (16) |
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| Section III Factors Affecting Mitochondrial Function |
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Chapter 24 Role of Carnosic Acid in Protection of Brain Mitochondria |
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293 | (16) |
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Marcos Roberto de Oliveira |
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Chapter 25 Mitochondrial Dysfunction and Its Impact on Oxidative Capacity of Muscle |
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309 | (10) |
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Chapter 26 The Effects of Resveratrol on the Brain Mitochondria |
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319 | (16) |
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Marcos Roberto de Oliveira |
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Chapter 27 Pathophysiology and Biomarkers of Mitochondrial Dysfunction Induced by Heavy Exercise |
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335 | (6) |
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Chapter 28 Mitochondrial Pathologies and Their Neuromuscular Manifestations |
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341 | (20) |
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Chapter 29 Mitochondrial Stress and Cellular Senescence |
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361 | (18) |
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Chapter 30 Role of Mitochondrial Dysfunction in Human Obesity |
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379 | (10) |
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Chapter 31 Roles of Melatonin in Maintaining Mitochondrial Welfare: Focus on Renal Cells |
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389 | (10) |
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Feres Jose Mocayar Martin |
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Chapter 32 Mitochondrial Dysfunction Affecting the Peripheral Nervous System in Diabetic Neuropathy and Avenues for Therapy |
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399 | (10) |
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Chapter 33 Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Metabolic Syndrome |
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409 | (16) |
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| Section IV Immunity and Toxicity |
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Chapter 34 Regulation of Antiviral Immunity by Mitochondrial Dynamics |
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425 | (18) |
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Chapter 35 Mitochondrial Dysfunction, Immune Systems, Their Diseases, and Possible Treatments |
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443 | (18) |
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Chapter 36 Organophosphorus Compound-Induced Mitochondrial Disruption |
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461 | (10) |
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Chapter 37 Mitochondrial Dysfunction in Friedreich Ataxia |
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471 | (6) |
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| Index |
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477 | |