| Preface |
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vii | |
| The Editors |
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ix | |
| Contributors |
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xi | |
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Chapter 1 Materials Science of DNA: An Introduction |
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1 | (12) |
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1.1 Naturally Occurring Organic Polymers |
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1 | (1) |
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1.2 Structures of Nucleic Acids |
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2 | (5) |
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1.3 Materials Science of DNA |
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7 | (6) |
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9 | (4) |
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Chapter 2 Nanostructures and Nanomaterials via DNA-Based Self-Assembly |
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13 | (36) |
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13 | (2) |
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2.2 Self-Assembly of DNA Nanostructures |
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15 | (15) |
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2.2.1 One-Dimensional DNA Nanostructures |
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16 | (2) |
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2.2.2 Two-Dimensional DNA Self-Assembly |
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18 | (4) |
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2.2.3 3D Self-Assembly of DNA Polyhedra |
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22 | (3) |
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2.2.4 3D Self-Assembly of Periodical DNA Crystals |
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25 | (2) |
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27 | (3) |
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2.3 DNA-Based Self-Assembly of Nanomaterials |
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30 | (11) |
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2.3.1 DNA-Based Self-Assembly of Gold Nanoparticles in One and Two Dimensions |
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30 | (2) |
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2.3.2 3D Ordering of Gold Nanoparticles with DNA |
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32 | (2) |
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2.3.3 DNA-Based Self-Assembly of Carbon Nanotubes |
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34 | (3) |
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2.3.4 DNA-Based Self-Assembly of Gold-Carbon Hybrid Nanostructures |
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37 | (4) |
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2.3.5 Molecular Lithography |
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41 | (1) |
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41 | (8) |
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43 | (1) |
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43 | (6) |
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Chapter 3 Intercalation of Organic Ligands as a Tool to Modify the Properties of DNA |
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49 | (28) |
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49 | (5) |
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3.2 Intercalation---General Principles |
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54 | (8) |
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3.2.1 Determination of the Intercalator-DNA Association |
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55 | (2) |
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57 | (3) |
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3.2.3 Dynamic Aspects of Intercalation |
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60 | (2) |
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3.3 Structural Changes of DNA upon Intercalation |
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62 | (15) |
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69 | (8) |
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Chapter 4 DNA and Carbon-Based Nanomaterials: Preparation and Properties of Their Composites |
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77 | (44) |
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77 | (2) |
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4.2 Deoxyribonucleic Acid (DNA) |
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79 | (1) |
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4.3 Carbon Nanotubes (CNTs) |
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80 | (2) |
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82 | (20) |
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83 | (8) |
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4.4.2 Encapsulation of DNA in CNTs |
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91 | (2) |
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4.4.3 Noncovalent Interactions Between DNA and CNTs |
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93 | (9) |
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102 | (2) |
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104 | (5) |
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4.7 Advantages and Disadvantages of Synthetic Approaches |
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109 | (1) |
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110 | (11) |
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112 | (1) |
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112 | (9) |
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Chapter 5 Electrical and Magnetic Properties of DNA |
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121 | (42) |
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5.1 Electrical Properties of DNA |
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121 | (13) |
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5.1.1 Charge Transport in Dry DNA |
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121 | (9) |
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5.1.2 Electrical Conductivity of DNA---A Summary |
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130 | (4) |
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5.2 Magnetic Properties of DNA |
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134 | (19) |
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134 | (1) |
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135 | (17) |
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5.2.3 Discotic Liquid Crystals as DNA-Mimicking Compounds |
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152 | (1) |
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153 | (10) |
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154 | (9) |
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Chapter 6 DNA Ionic Liquid |
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163 | (16) |
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163 | (1) |
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6.2 DNA and Ionic Liquid Mixture |
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164 | (1) |
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6.3 Ionic liquidized DNA-Inner Column |
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164 | (6) |
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6.3.1 Low-Molecular-Weight Model Compounds |
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165 | (2) |
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6.3.2 Ionic liquidized Bases in DNA |
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167 | (3) |
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6.4 Ionic liquidized DNA-Outer Column |
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170 | (6) |
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176 | (3) |
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176 | (1) |
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176 | (3) |
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Chapter 7 DNA-Surfactant Thin-Film Processing and Characterization |
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179 | (52) |
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180 | (1) |
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180 | (5) |
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180 | (1) |
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7.2.2 Precipitation with CTMA Surfactant |
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181 | (1) |
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7.2.3 Preparation of DNA-CTMA Films |
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182 | (1) |
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7.2.3.1 Non-Cross-Linked DNA-CTMA Films |
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182 | (1) |
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7.2.3.2 Cross-Linked DNA-CTMA Films |
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183 | (1) |
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7.2.3.3 DNA-CTMA-Chromophore Films |
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184 | (1) |
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185 | (1) |
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7.3 Material Characterization |
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185 | (5) |
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185 | (2) |
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7.3.2 Index of Refraction |
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187 | (1) |
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187 | (1) |
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187 | (2) |
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189 | (1) |
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189 | (1) |
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7.4 RF Electrical Characterization |
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190 | (13) |
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7.4.1 Capacitive Test Structure |
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190 | (4) |
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7.4.1.1 Experimental Procedure |
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194 | (2) |
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7.4.1.2 Results and Analysis |
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196 | (4) |
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7.4.1.3 Capacitance Measurements |
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200 | (1) |
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7.4.2 Electric Force Microscopy |
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201 | (2) |
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7.5 DC Resistivity Studies |
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203 | (28) |
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203 | (2) |
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7.5.2 Measurement Technique |
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205 | (3) |
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208 | (4) |
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212 | (1) |
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7.5.4.1 DNA Compared to Nonbiopolymers |
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212 | (3) |
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215 | (1) |
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7.5.4.3 Effect of Humidity and Measurement Accuracy |
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216 | (2) |
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7.5.4.4 DNA with Conductive Dopants |
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218 | (2) |
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220 | (4) |
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224 | (2) |
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226 | (1) |
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226 | (5) |
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Chapter 8 Applications of DNA to Photonics and Biomedicals |
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231 | (24) |
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231 | (1) |
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8.2 Photonic Applications of DNA |
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232 | (13) |
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8.2.1 Stability Improvements of DNA Photonic Devices by Blending with Synthetic Polymers |
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233 | (1) |
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233 | (2) |
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8.2.1.2 Results and Discussion |
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235 | (2) |
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8.2.2 Chelation of DNA with Novel Metals or Rare Earth Metal Compounds |
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237 | (5) |
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242 | (3) |
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8.3 Biomedical Application of DNA Films |
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245 | (5) |
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8.3.1 UV Cross-Linking of DNA Films |
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245 | (1) |
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8.3.2 Cell Culture on DNA Films |
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246 | (1) |
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8.3.3 Wound-Healing Effect of DNA and Cross-Linked DNA Films |
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247 | (3) |
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250 | (5) |
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253 | (2) |
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Chapter 9 DNA-Based Thin-Film Devices |
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255 | (36) |
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9.1 All-DNA-Based Electro-Optic Waveguide Modulator |
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256 | (7) |
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256 | (1) |
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9.1.2 Electro-Optic Coefficient |
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257 | (2) |
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9.1.3 Device Testing and Performance |
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259 | (3) |
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262 | (1) |
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9.2 Field-Effect Transistors |
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263 | (10) |
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9.2.1 Principles of Operation |
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263 | (1) |
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264 | (1) |
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265 | (1) |
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9.2.2.2 Sensor Applications |
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265 | (1) |
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9.2.3 DNA Biopolymer as the Semiconducting Layer |
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266 | (1) |
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9.2.3.1 Measurement Setup |
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266 | (1) |
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9.2.3.2 Initial Bottom-Gate BioFET |
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267 | (4) |
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9.2.3.3 Improvements to the BioFET |
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271 | (2) |
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9.3 Development of a BioLED: DNA as an Electron-Blocking Layer in Organic Light-Emitting Diodes |
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273 | (13) |
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9.3.1 Materials Used for the Fabrication of BioLEDs |
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273 | (1) |
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9.3.1.1 Emitting Molecules Used in BioLEDs |
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273 | (1) |
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9.3.1.2 Hole Transport Layers Used in BioLEDs |
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273 | (1) |
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9.3.1.3 Hole Blocking Layer Used in BioLEDs |
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274 | (1) |
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9.3.1.2 ETL Used in BioLEDs |
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274 | (1) |
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9.3.1.3 EBL Used in BioLEDs |
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274 | (2) |
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9.3.2 Fabrication of BioLEDs |
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276 | (1) |
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9.3.2.1 Anode Patterning and Deposition |
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276 | (1) |
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9.3.2.2 Solvent-Based Deposition of HTL and EBL |
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277 | (1) |
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9.3.2.3 Molecular Beam Deposition |
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277 | (1) |
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9.3.3 Green (Alq3)-Emitting BioLED Results |
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278 | (2) |
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9.3.4 Comparison of DNA-CTMA to Other Optoelectronic Polymers |
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280 | (3) |
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9.3.5 Lifetime of BioLED and Baseline Devices |
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283 | (3) |
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286 | (5) |
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286 | (5) |
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Chapter 10 Nucleic Acids-Based Biosensors |
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291 | (20) |
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291 | (2) |
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10.2 DNA-Based Biosensors for Diagnostics |
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293 | (4) |
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10.3 DNA-Based Biosensor for Environmental Application |
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297 | (2) |
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10.4 New Frontiers in Nucleic Biosensors: Aptamer-Based Biosensors |
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299 | (12) |
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305 | (6) |
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Chapter 11 Materials Science of DNA---Conclusions and Perspectives |
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311 | (8) |
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| Index |
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