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| Preface | v | ||
| Contributors | ix | ||
| 1. Overview on Opioid-Induced Hyperalgesia | 1 | ||
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| 2. Cellular Mechanisms Underlying Morphine Analgesic Tolerance and Hyperalgesia | 9 | ||
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| 3. Overview on Clinical Features of Opioid-Induced Hyperalgesia | 21 | ||
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| 4. Clinical Assessment Tools: Quantitative Sensory Testing | 38 | ||
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| 5. Opioid Tolerance, Dependence, and Hyperalgesia | 61 | ||
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| 6. Challenging Clinical Issues on the Interaction Between Addiction and Hyperalgesia | 74 | ||
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| 7. Practical Management of Opioid-Induced Hyperalgesia in the Primary Care Setting | 95 | ||
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| 8. Managing Opioid-Induced Hyperalgesia in the Perioperative Period | 103 | ||
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| 9. Role of Ketamine in Managing Opioid-Induced Hyperalgesia | 124 | ||
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| 10. Role of Opioid Rotation and Tapering in Managing Opioid-Induced Hyperalgesia | 134 | ||
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| 11. Role of Adjuvant Medications in Managing Opioid-Induced Hyperalgesia | 164 | ||
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| 12. Clinical Implications of Opioid-Induced Hyperalgesia | 174 | ||
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| Index | 181 |