This book examines targeted drug delivery systems covering molecular targeting mechanisms, nanotechnology-based carriers, and controlled release technologies. The analysis includes liposomes, dendrimers, polymer-based systems, and encapsulation techniques for enhanced bioavailability and reduced toxicity, and also includes:
- Comprehensive examination of targeted drug delivery systems covering molecular targeting mechanisms, biological processes, and therapeutic strategy optimization
- Analysis of advanced nanotechnology-based drug carriers including liposomes, dendrimers, and polymer-based delivery systems for precision medicine applications
- Investigation of encapsulation materials and techniques for controlled drug release with emphasis on bioavailability enhancement and systemic toxicity reduction
- Assessment of regulatory considerations and clinical trial methodologies for drug delivery system development and approval processes
- Study of personalized medicine approaches through targeted delivery technologies and their impact on therapeutic outcomes
The case studies help demonstrate precision targeting strategies, therapeutic outcome improvements, and systematic approaches to drug formulation, making it an important reading for understanding modern pharmaceutical technologies and their role in advancing healthcare through targeted therapeutic interventions.
This title has been co-published with Manakin Press. T&F does not sell or distribute the print editions in Bangladesh, Bhutan, India, Nepal, Pakistan, and Sri lanka.
This book examines targeted drug delivery systems covering molecular targeting mechanisms, nanotechnology-based carriers, and controlled release technologies including liposomes, dendrimers, polymer-based systems, and encapsulation techniques for enhanced bioavailability and reduced toxicity.
PART 1: Drug Delivery Technologies
Target Oriented Drug Delivery Systems
Molecular Basis of Targeted Drug Delivery System
Drug Release and Uptake Phenomenon
Drug Encapsulation Techniques and Materials
Nanomaterials
Drug Delivery Factors
Factors Affecting Drug Loading and Release
Techniques to Measure the Degree of Loading and Release Efficiency,
Metabolism and Excretion of Drug Delivery Carriers
Liposomes
Monomers
Resealed Erythrocyte as Drug Delivery System
Nanoparticulate System
Solid Lipid Nanoparticles
Dendrimers
Organogels
Multiple Emulsions
Nano Emulsions
Overview and Application of Aquasomes, Pharmacosomes, Liquid Crystalline
Systems, Protein and Peptide Based Drug Delivery Systems
Polymers in Drug Encapsulation and Drug Delivery
Polymers in Drug Encapsulation and Drug Delivery
PART 2: Pharmaceutical Technologies Development
21. Drug Discovery, Lead Identification and Lead Optimization, Chemical,
Pharmaceutical and Clinical Technology Development
22. Investigational New Drug and It's Applications
23. Clinical Trials and Its Phases
24. A Brief Overview and Recent Advances in Pilot Plant Scale-Up Techniques
Navneet Sharma serves as Scientist of pharmaceutical chemistry, biomaterials, and contamination sciences. He holds an M. Pharm from JSS University, a Postgraduate Diploma in Drug Regulatory Affairs from Jamia Hamdard, and a Ph.D. in Pharmaceutical Sciences from the University of Delhi. His doctoral work at INMAS (DRDO) focused on developing topical formulations for chemical, biological, radiological, and nuclear (CBRN) skin decontamination, incorporating toxicological assessments and cellular studies. Dr. Sharmas postdoctoral research at IIT Delhi led to the development of zinc titanate-based biodegradable materials for CBRN decontamination, integrating nanomaterials for improved efficacy and sustainability. Her research focuses on molecular modeling, drug-molecule interactions, and water remediation. She has published extensively, contributed to international collaborations, and holds multiple patents.
Mallika Pathak is Professor at the Department of Chemistry, Miranda House, University of Delhi, Delhi, India. He has received numerous honors, including the Australian Leadership Award Fellowship (2013), 'Most Promising Innovation' (2016), and the 'Teaching Excellence Award for Innovation' (2015) from the University of Delhi, India.
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